Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 14/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | BCL6 | P41182 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999444 | 0.87 | KDR (0.39) | KDRMAPKAPK2RIPK2 | |
| SCHEMBL30180298 | 0.87 | KDR (0.39) | KDRMAPKAPK2RIPK2 | |
| SCHEMBL23999399 | 0.86 | MAPKAPK2 (0.42) | KDRMAPKAPK2RIPK2 | |
| SCHEMBL23999766 | 0.84 | MAPKAPK2 (0.38) | KDRMAPKAPK2 | |
| SCHEMBL23999591 | 0.83 | KDR (0.39) | KDREGFRMAPKAPK2RIPK2 | |
| SCHEMBL25484070 | 0.80 | SLC2A1 (0.33) | KDR | |
| SCHEMBL23999588 | 0.80 | PRMT5 (0.36) | KDRPRMT5 | |
| SCHEMBL23999409 | 0.79 | LRRK2 (0.40) | MAPKAPK2RIPK2 | |
| SCHEMBL23999480 | 0.78 | DNMT1 (0.38) | — | |
| SCHEMBL23999593 | 0.76 | SLC2A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226519-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2021-11-11 | — | — | WO | disclosed |