Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 15/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 5/20 | 0.38 |
| ▸ | MET | P08581 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25495797 | 0.91 | KDR (0.37) | KDRMAPKAPK2 | |
| SCHEMBL23999610 | 0.89 | KDR (0.47) | KDRMAPKAPK2 | |
| SCHEMBL30180419 | 0.89 | KDR (0.47) | KDRMAPKAPK2 | |
| SCHEMBL23999461 | 0.85 | KDR (0.49) | KDRMAPKAPK2 | |
| SCHEMBL23999406 | 0.82 | MAPKAPK2 (0.52) | KDRMAPKAPK2 | |
| SCHEMBL23999659 | 0.82 | L3MBTL1 (0.43) | KDR | |
| SCHEMBL30180305 | 0.80 | KDR (0.40) | KDRMAPKAPK2 | |
| SCHEMBL23999478 | 0.80 | KDR (0.40) | KDRMAPKAPK2 | |
| SCHEMBL23999476 | 0.80 | KDR (0.39) | KDRMAPKAPK2 | |
| SCHEMBL30180227 | 0.80 | KDR (0.39) | KDRMAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226519-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2021-11-11 | — | — | WO | disclosed |