Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.62 |
| ▸ | SCN4A | P35499 | 1/20 | 0.58 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165837 | 0.91 | SCN4A (0.74) | KMT2AKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL4554306 | 0.83 | L3MBTL1 (0.59) | KMT2AKDM4EALDH1A1MAPTGAA | |
| SCHEMBL30201670 | 0.83 | GFER (0.68) | KMT2AKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL15718835 | 0.81 | KMT2A (0.63) | KMT2AKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL17560882 | 0.81 | PRMT5 (0.61) | KMT2AKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL17560984 | 0.81 | SCN4A (0.82) | KMT2AKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL15718834 | 0.81 | KMT2A (0.63) | KMT2AKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL11878478 | 0.81 | KDM4E (0.53) | KMT2AKDM4EALDH1A1MAPTGAA | |
| SCHEMBL17560884 | 0.81 | PRMT5 (0.61) | KMT2AKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL5614884 | 0.81 | KDM4E (0.81) | KDM4EALDH1A1MAPTGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2991968-B1 | COMPOUNDS AND METHODS OF TREATING INFECTIONS | NEOCULI PTY LTD (AU) | 2021-11-10 | — | — | EP | disclosed |