SCHEMBL2400263

SCHEMBL2400263

CC[Si](CCCN1CCNCC1)(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 2/20 0.42
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SIGMAR1 Q99720 1/20 0.37
PIM1 P11309 1/20 0.35
POLB P06746 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GNAO1 P09471 4/20 0.35
GNAI3 P08754 3/20 0.35
GNAI1 P63096 3/20 0.35
SOD3 P08294 2/20 0.34
HRH2 P25021 2/20 0.34
HRH1 P35367 2/20 0.34
HRH3 Q9Y5N1 1/20 0.33
TLR8 Q9NR97 1/20 0.33
TLR7 Q9NYK1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11655299 0.88 CXCR4 (0.41) CXCR4MEN1KMT2ASIGMAR1PIM1
SCHEMBL2398826 0.85 CXCR4 (0.41) CXCR4MEN1KMT2ASIGMAR1POLB
SCHEMBL14015585 0.85 CXCR4 (0.41) CXCR4MEN1KMT2ASIGMAR1PIM1
SCHEMBL2851026 0.82 HRH3 (0.45) POLBSMN1; SMN2HRH1HRH3
SCHEMBL613997 0.82 HRH3 (0.45) POLBSMN1; SMN2HRH1HRH3
SCHEMBL11657398 0.82 CXCR4 (0.39) CXCR4MEN1KMT2ASIGMAR1HSD17B10
SCHEMBL465021 0.80 CXCR4 (0.46) CXCR4MEN1KMT2ASIGMAR1PIM1
SCHEMBL21111280 0.80
SCHEMBL614018 0.79 SMN1; SMN2 (0.48) SIGMAR1PIM1SMN1; SMN2HRH3
SCHEMBL28394858 0.79 CXCR4 (0.39) CXCR4MEN1KMT2ASIGMAR1PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108624105-B Preparation method of water-soluble antifouling anti-doodling auxiliary agent 太仓中化环保化工有限公司 2020-10-20 CN claimed
CN-108624105-A A kind of preparation method of the antifouling anti-graffiti auxiliary agent of water solubility 太仓中化环保化工有限公司 2018-10-09 CN claimed
CN-108753013-B Water-soluble antifouling anti-doodling auxiliary agent and application thereof 太仓中化环保化工有限公司 2020-12-01 CN disclosed
CN-108624105-B Preparation method of water-soluble antifouling anti-doodling auxiliary agent 太仓中化环保化工有限公司 2020-10-20 CN disclosed
US-10189987-B2 Pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-01-29 US disclosed
CN-108624105-A A kind of preparation method of the antifouling anti-graffiti auxiliary agent of water solubility 太仓中化环保化工有限公司 2018-10-09 CN disclosed
EP-3064546-B1 PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-08-29 EP disclosed
US-9932460-B2 Rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2018-04-03 US disclosed
US-9845385-B2 Rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-12-19 US disclosed
US-20160264772-A1 PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-09-15 US disclosed
EP-2674457-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2016-09-14 EP disclosed
US-20130303679-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-11-14 US disclosed
EP-2597117-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2013-05-29 EP disclosed
US-20130079464-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-03-28 US disclosed
US-8318858-B2 Conjugated diene polymer, conjugated diene polymer composition, and method for producing conjugated diene polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-11-27 US disclosed
US-20120149806-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. 2012-06-14 US disclosed
EP-2463310-A1 Rubber composition and pneumatic tire Sumitomo Rubber Industries, Ltd. (JP) 2012-06-13 EP disclosed
US-20110237737-A1 CONJUGATED DIENE POLYMER RUBBER, AND CONJUGATED DIENE POLYMER RUBBER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-09-29 US disclosed
US-20100056713-A1 CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-04 US disclosed
US-4098840-A THERMOSETTING RESIN COMPOSITION JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 1978-07-04 US disclosed