SCHEMBL2398826

SCHEMBL2398826

CCO[Si](CC)(CCCN1CCNCC1)OCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 2/20 0.41
SIGMAR1 Q99720 1/20 0.36
POLB P06746 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
GNAO1 P09471 4/20 0.34
GNAI3 P08754 3/20 0.34
GNAI1 P63096 3/20 0.34
HSD17B10 Q99714 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
DRD2 P14416 1/20 0.34
DRD3 P35462 1/20 0.34
SOD3 P08294 2/20 0.33
HRH2 P25021 2/20 0.33
HRH1 P35367 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
RAB9A P51151 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11660650 0.89 CXCR4 (0.40) CXCR4SIGMAR1POLBSMN1; SMN2GNAO1
SCHEMBL11657398 0.87 CXCR4 (0.39) CXCR4SIGMAR1GNAO1GNAI3GNAI1
SCHEMBL2400263 0.85 CXCR4 (0.42) CXCR4SIGMAR1POLBSMN1; SMN2GNAO1
SCHEMBL1458452 0.83 HRH3 (0.43) SMN1; SMN2KDM4EALDH1A1HRH3
SCHEMBL614544 0.83 HRH3 (0.43) SMN1; SMN2KDM4EALDH1A1HRH3
SCHEMBL497398 0.83 PAOX (0.36) SIGMAR1GNAO1GNAI3GNAI1DRD3
SCHEMBL2401145 0.83 CXCR4 (0.43) CXCR4SIGMAR1POLBSMN1; SMN2GNAO1
SCHEMBL774670 0.81 CXCR4 (0.42) CXCR4SIGMAR1POLBSMN1; SMN2GNAO1
SCHEMBL3358618 0.81 CXCR4 (0.42) CXCR4SIGMAR1POLBSMN1; SMN2GNAO1
SCHEMBL4063049 0.81 CXCR4 (0.42) CXCR4SIGMAR1POLBSMN1; SMN2GNAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108624105-B Preparation method of water-soluble antifouling anti-doodling auxiliary agent 太仓中化环保化工有限公司 2020-10-20 CN claimed
CN-108624105-A A kind of preparation method of the antifouling anti-graffiti auxiliary agent of water solubility 太仓中化环保化工有限公司 2018-10-09 CN claimed
CN-108753013-B Water-soluble antifouling anti-doodling auxiliary agent and application thereof 太仓中化环保化工有限公司 2020-12-01 CN disclosed
CN-108624105-B Preparation method of water-soluble antifouling anti-doodling auxiliary agent 太仓中化环保化工有限公司 2020-10-20 CN disclosed
US-10189987-B2 Pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-01-29 US disclosed
CN-108753013-A A kind of antifouling anti-graffiti auxiliary agent of water solubility and its application 太仓中化环保化工有限公司 2018-11-06 CN disclosed
CN-108624105-A A kind of preparation method of the antifouling anti-graffiti auxiliary agent of water solubility 太仓中化环保化工有限公司 2018-10-09 CN disclosed
EP-3064546-B1 PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-08-29 EP disclosed
US-9932460-B2 Rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2018-04-03 US disclosed
US-9845385-B2 Rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-12-19 US disclosed
US-20160264772-A1 PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-09-15 US disclosed
US-20130303679-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-11-14 US disclosed
EP-2597117-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2013-05-29 EP disclosed
US-20130079464-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-03-28 US disclosed
US-8318858-B2 Conjugated diene polymer, conjugated diene polymer composition, and method for producing conjugated diene polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-11-27 US disclosed
US-20120149806-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. 2012-06-14 US disclosed
EP-2463310-A1 Rubber composition and pneumatic tire Sumitomo Rubber Industries, Ltd. (JP) 2012-06-13 EP disclosed
US-20110237737-A1 CONJUGATED DIENE POLYMER RUBBER, AND CONJUGATED DIENE POLYMER RUBBER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-09-29 US disclosed
US-20100056713-A1 CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-04 US disclosed
US-4098840-A THERMOSETTING RESIN COMPOSITION JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 1978-07-04 US disclosed