Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7856967 | 0.85 | MAOB (0.48) | MAOBNAMPTHIF1ANPC1RAB9A | |
| SCHEMBL24562817 | 0.81 | PARP1 (0.46) | MAOBNAMPTNPC1RAB9AEGLN1 | |
| SCHEMBL22854273 | 0.77 | NPC1 (0.45) | NAMPTNPC1RAB9A | |
| SCHEMBL13002904 | 0.74 | KIT (0.53) | NAMPTNPC1RAB9AKMT2A | |
| SCHEMBL14429972 | 0.72 | ALDH1A1 (0.44) | NPC1RAB9A | |
| SCHEMBL16887934 | 0.71 | MAOB (0.69) | MAOBHIF1ANPC1RAB9AEGLN1 | |
| SCHEMBL23417254 | 0.71 | EGLN1 (0.51) | MAOBHIF1ANPC1RAB9AKMT2A | |
| SCHEMBL8973342 | 0.71 | MAOB (0.81) | MAOBHIF1ANPC1RAB9AKMT2A | |
| SCHEMBL21379406 | 0.70 | NAMPT (0.48) | MAOBNAMPTHIF1AEGLN1 | |
| SCHEMBL3000781 | 0.70 | MAOB (0.51) | MAOBHIF1ANPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226262-A1 | BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF | NURIX THERAPEUTICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |