Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295660 | 0.79 | KDM1A (0.38) | HTR2CKDM1AHTR2AHTR2BALDH1A1 | |
| SCHEMBL2330639 | 0.79 | SMN1; SMN2 (0.38) | HTR2CHTR2AHTR2BHRH3 | |
| SCHEMBL24005492 | 0.79 | PRCP (0.35) | PRCP | |
| Hydrochloric Acid SCHEMBL31444543 | 0.78 | SMN1; SMN2 (0.37) | HTR2CKDM1AHTR2AHTR2BHRH3 | |
| SCHEMBL2331878 | 0.74 | PRCP (0.40) | HTR2BALDH1A1PRCP | |
| SCHEMBL22423680 | 0.74 | HTR2C (0.57) | HTR2CKDM1ADDB1CRBNHTR2A | |
| SCHEMBL27454929 | 0.73 | HTR2C (0.37) | HTR2CHTR2AHTR2B | |
| SCHEMBL13189805 | 0.73 | HTR2C (0.50) | HTR2CKDM1ADDB1CRBNHTR2A | |
| SCHEMBL10331631 | 0.73 | HTR2C (0.50) | HTR2CKDM1ADDB1CRBNHTR2A | |
| SCHEMBL14290349 | 0.73 | HTR2C (0.50) | HTR2CKDM1ADDB1CRBNHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021223736-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-11-11 | — | — | WO | disclosed |