SCHEMBL2331878

SCHEMBL2331878

c1ccc(C2CSCCN2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRCP P42785 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
NPC1 O15118 1/20 0.40
SLC18A3 Q16572 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
TSHR P16473 1/20 0.35
SLC6A2 P23975 1/20 0.34
ADRA1A P35348 1/20 0.34
HTR2B P41595 1/20 0.34
SLC6A3 Q01959 1/20 0.34
GAA P10253 1/20 0.34
USP2 O75604 1/20 0.34
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
ALOX12 P18054 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2330365 0.81 PRCP (0.37) PRCPTSHRALDH1A1MAPTSMN1; SMN2
SCHEMBL2335474 0.80 CHRNB2 (0.59) MEN1KMT2AALDH1A1SMN1; SMN2CHRNB2
SCHEMBL11155868 0.79 PRCP (0.42) PRCPMEN1KMT2ANPC1SLC18A3
SCHEMBL553649 0.79 GID4 (0.44) MEN1KMT2ATSHRSLC6A2HTR2B
SCHEMBL2327908 0.77 MAOA (0.46) MEN1KMT2AGAAALDH1A1RAB9A
SCHEMBL2333392 0.77 HTR2C (0.45) MEN1KMT2AGAAALDH1A1MAPT
SCHEMBL26086367 0.76 HTR2C (0.50) MEN1KMT2ANPC1HTR2BGAA
SCHEMBL5537125 0.76 HTR2C (0.50) MEN1KMT2ASIGMAR1HTR2BALDH1A1
SCHEMBL24005476 0.74 HTR2C (0.43) PRCPHTR2BALDH1A1
SCHEMBL28027597 0.74 MEN1 (0.38) MEN1KMT2AHTR2BGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036605-A Antagonists of GPR39 proteins 俄勒冈健康科学大学 2026-05-15 CN disclosed
EP-4688889-A1 ENAMINES AS INITIATORS IN THE CURING OF FREE-RADICALLY CURING REACTIVE RESINS FOR CHEMICAL FASTENING Hilti Aktiengesellschaft (LI) 2026-02-11 EP disclosed
WO-2024208627-A1 ENAMINES AS INITIATORS IN THE CURING OF FREE-RADICALLY CURING REACTIVE RESINS FOR CHEMICAL FASTENING HILTI AKTIENGESELLSCHAFT (LI) 2024-10-10 WO disclosed
EP-4442721-A1 ENAMINES AS INITIATORS IN THE CURING OF RADICALLY HARDENING REACTIVE RESINS FOR CHEMICAL FIXING Hilti Aktiengesellschaft (LI) 2024-10-09 EP disclosed
US-20230174484-A1 ANTAGONISTS OF GPR39 PROTEIN UNIV OREGON HEALTH & SCIENCE (US) 2023-06-08 US disclosed
CN-115996908-A Antagonists of GPR39 proteins 俄勒冈健康科学大学 2023-04-21 CN disclosed
EP-4143163-A1 ANTAGONISTS OF GPR39 PROTEIN Oregon Health & Science University (US) 2023-03-08 EP disclosed
US-11566025-B2 Viral replication inhibitors KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-01-31 US disclosed
WO-2021222858-A1 ANTAGONISTS OF GPR39 PROTEIN OREGON HEALTH & SCIENCE UNIVERSITY (US) 2021-11-04 WO disclosed
CN-105283451-B Novel inhibitors of viral replication 鲁汶天主教大学 2021-01-26 CN disclosed
US-5652247-A VASOPRESSIN ANTAGONIST OTSUKA PHARMACEUTICAL CO., LTD (JP) 1997-07-29 US disclosed
US-5436254-A Vaopressin antagonists OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) 1995-07-25 US disclosed
US-5358949-A Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-10-25 US disclosed
CN-1091288-A The oxytocin antagonist OTSUKA PHARMA CO LTD (JP) 1994-08-31 CN disclosed
EP-0602209-A1 OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-06-22 EP disclosed
EP-0382185-B1 Carbostyril derivatives OTSUKA PHARMA CO LTD (JP) 1994-06-15 EP disclosed
WO-1994001113-A1 OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1994-01-20 WO disclosed
US-5225402-A Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-07-06 US disclosed
CN-1046529-A Carbostyril derivative OTSUKA PHARMA CO LTD (JP) 1990-10-31 CN disclosed
EP-0236140-A2 Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1987-09-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11566025-B2 Viral replication inhibitors EIF2AK2, MAVS, ZC3HAV1 PRCP 707/4885MEN1 3390/4885KMT2A 2425/4885
US-20230174484-A1 ANTAGONISTS OF GPR39 PROTEIN GPR39, GPR139, GPR119 PRCP 1700/4885MEN1 3377/4885KMT2A 4013/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.