Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24005989 | 0.93 | MAPT (0.46) | MAPK10MAPTGSK3BMAPK14MTOR | |
| SCHEMBL24006300 | 0.92 | MAPK10 (0.52) | MAPKAPK2MAPK10MAPTGSK3BMAPK14 | |
| SCHEMBL24005997 | 0.92 | MAPKAPK2 (0.47) | MAPKAPK2MAPK10MAPTMAPK14MTOR | |
| SCHEMBL30180401 | 0.88 | MAPT (0.49) | MAPKAPK2MAPK10MAPTGSK3BMAPK14 | |
| SCHEMBL23999438 | 0.88 | MAPT (0.49) | MAPKAPK2MAPK10MAPTGSK3BMAPK14 | |
| SCHEMBL24005987 | 0.85 | MAPK10 (0.53) | MAPK10MAPTGSK3BMAPK14MAPK9 | |
| SCHEMBL24005998 | 0.84 | MAPT (0.47) | MAPK10MAPTMAPK14MTORSMN1; SMN2 | |
| SCHEMBL23999785 | 0.83 | MAPT (0.54) | MAPKAPK2MAPK10MAPTSLC2A1MAPK9 | |
| SCHEMBL30180392 | 0.83 | MAPT (0.54) | MAPKAPK2MAPK10MAPTSLC2A1MAPK9 | |
| SCHEMBL24006299 | 0.83 | DNMT1 (0.56) | MAPKAPK2MAPK10MAPTMAPK14SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081845-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2021226477-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2021-11-11 | — | — | WO | disclosed |