Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.39 |
| ▸ | CDC25A | P30304 | 2/20 | 0.38 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | CDC25C | P30307 | 2/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4859113 | 0.90 | CDC25A (0.49) | S100A4CDC25ACDC25BCDC25CMALT1 | |
| SCHEMBL2400277 | 0.83 | RET (0.40) | S100A4CDC25ACDC25BCDC25CALDH1A1 | |
| SCHEMBL4865657 | 0.78 | CDC25A (0.52) | CDC25ACDC25BCDC25CMALT1ALDH1A1 | |
| SCHEMBL2404183 | 0.78 | CDC25A (0.53) | CDC25ACDC25BCDC25CALDH1A1PRMT1 | |
| SCHEMBL2400614 | 0.77 | CDC25A (0.62) | S100A4CDC25ACDC25BCDC25CMALT1 | |
| SCHEMBL1919013 | 0.74 | CDC25A (0.52) | CDC25ACDC25BCDC25CMALT1ALDH1A1 | |
| SCHEMBL1918571 | 0.74 | CDC25A (0.52) | CDC25ACDC25BCDC25CMALT1ALDH1A1 | |
| SCHEMBL2399120 | 0.73 | ALOX5 (0.45) | CDC25ACDC25BIDO1TDO2 | |
| SCHEMBL4865048 | 0.73 | CDC25B (0.48) | S100A4CDC25ACDC25BCDC25CMALT1 | |
| SCHEMBL4865798 | 0.71 | MALT1 (0.53) | S100A4CDC25ACDC25BCDC25CMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017637-B2 | Inhibitors of cdc phosphatases | IPSEN PHARMA S.A.S. (FR) | 2011-09-13 | — | — | US | disclosed |
| EP-1831209-B1 | CDC25 PHOSPHATASE INHIBITORS | IPSEN PHARMA (FR) | 2009-08-12 | — | — | EP | disclosed |