Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCAT | P04180 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GLP1R | P43220 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.33 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24008575 | 0.93 | LCAT (0.41) | LCATKCNH2CTSBCTSSCTSK | |
| SCHEMBL30287704 | 0.88 | LCAT (0.38) | LCATKCNH2CTSBCTSSCTSK | |
| SCHEMBL24008489 | 0.88 | LCAT (0.38) | LCATKCNH2CTSBCTSSCTSK | |
| SCHEMBL24008444 | 0.88 | LCAT (0.38) | LCATKCNH2CTSBCTSSCTSK | |
| SCHEMBL30287747 | 0.88 | LCAT (0.38) | LCATKCNH2CTSBCTSSCTSK | |
| SCHEMBL22668724 | 0.83 | LCAT (0.35) | LCATKCNH2CTSBCTSSCTSK | |
| SCHEMBL24008942 | 0.82 | LCAT (0.40) | LCATKCNH2CTSBCTSSCTSK | |
| SCHEMBL30287689 | 0.81 | LCAT (0.41) | LCATKCNH2CTSBCTSSCTSK | |
| SCHEMBL24008578 | 0.81 | LCAT (0.41) | LCATKCNH2CTSBCTSSCTSK | |
| SCHEMBL30287722 | 0.81 | LCAT (0.41) | LCATKCNH2CTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021224864-A1 | NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2021-11-11 | — | — | WO | disclosed |