SCHEMBL2400889

SCHEMBL2400889

NN[PbH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL88905 0.67
Hydrochloric Acid SCHEMBL27951559 0.62
SCHEMBL27298903 0.62
SCHEMBL51759 0.61
SCHEMBL2671521 0.58
SCHEMBL18115791 0.58
Ammonia Solution, Strong SCHEMBL11261565 0.55
SCHEMBL371051 0.55
Ammonia Solution, Strong SCHEMBL2019243 0.55
Ammonia Solution, Strong SCHEMBL1357155 0.55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113647408-B Antiviral agent, coating composition, resin composition, and antiviral product 东亚合成株式会社 2024-05-28 CN disclosed
CN-113647408-A Antiviral agent, coating composition, resin composition, and antiviral product 东亚合成株式会社 2021-11-16 CN disclosed
EP-2920175-B1 TRIAZOLOPYRIDAZINE DERIVATIVES AS BROMODOMAIN INHIBITORS BOEHRINGER INGELHEIM INT (DE) 2018-10-24 EP disclosed
CN-108697094-A Antiviral agent, coating composition, resin composition, and antiviral product 东亚合成株式会社 2018-10-23 CN disclosed
WO-2017133701-A1 CERTAIN PROTEIN KINASE INHIBITORS SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) 2017-08-10 WO disclosed
CN-106458856-A Inhibitors of histone lysine specific demethylase (lsd1) and histone deacetylases (hdacs) 约翰霍普金斯大学 2017-02-22 CN disclosed
US-9422290-B2 Triazolopyridazine BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2016-08-23 US disclosed
EP-2920175-A1 TRIAZOLOPYRIDAZINE Boehringer Ingelheim International GmbH (DE) 2015-09-23 EP disclosed
WO-2014076146-A1 TRIAZOLOPYRIDAZINE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2014-05-22 WO disclosed
US-20140135336-A1 TRIAZOLOPYRIDAZINE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2014-05-15 US disclosed
US-8394952-B2 Dihydrodiazepines useful as inhibitors of protein kinases VERTEX PHARMACEUTICALS INCORPORATED (US) 2013-03-12 US disclosed
US-20120149898-A1 DIHYDRODIAZEPINES USEFUL AS INHIBITORS OF PROTEIN KINASES VERTEX PHARMACEUTICALS INCORPORATED (US) 2012-06-14 US disclosed
US-8022202-B2 Dihydrodiazepines useful as inhibitors of protein kinases VERTEX PHARMACEUTICALS INCORPORATED (US) 2011-09-20 US disclosed
EP-1983987-B1 DIHYDRODIAZEPINES USEFUL AS INHIBITORS OF PROTEIN KINASES VERTEX PHARMA (US) 2010-09-01 EP disclosed
US-20100190765-A1 DIHYDRODIAZEPINES USEFUL AS INHIBITORS OF PROTEIN KINASES VERTEX PHARMACEUTICALS INCORPORATED (US) 2010-07-29 US disclosed
US-7622463-B2 Dihydrodiazepines useful as inhibitors of protein kinases VERTEX PHARMACEUTICALS INCORPORATED (US) 2009-11-24 US disclosed
EP-1983987-A2 DIHYDRODIAZEPINES USEFUL AS INHIBITORS OF PROTEIN KINASES Vertex Pharmaceuticals Incorporated (US) 2008-10-29 EP disclosed
US-20080167289-A1 Dihydrodiazepines useful as inhibitors of protein kinases VERTEX PHARMACEUTICALS INCORPORATED 2008-07-10 US disclosed
WO-2007095188-A2 DIHYDRODIAZEPINES USEFUL AS INHIBITORS OF PROTEIN KINASES VERTEX PHARMACEUTICALS INCORPORATED (US) 2007-08-23 WO disclosed
US-5693599-A Flux washing agent MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1997-12-02 US disclosed