⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2400939 | 1.00 | — | — | |
| SCHEMBL322831 | 0.68 | — | — | |
| SCHEMBL43443 | 0.68 | — | — | |
| SCHEMBL322830 | 0.68 | — | — | |
| SCHEMBL27368989 | 0.68 | — | — | |
| SCHEMBL10636727 | 0.68 | — | — | |
| SCHEMBL831105 | 0.68 | — | — | |
| SCHEMBL9069089 | 0.64 | — | — | |
| SCHEMBL4105220 | 0.64 | ALDH1A1 (0.61) | — | |
| SCHEMBL1677666 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012466-B2 | Immunogenic compositions for activating γδ T cells | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2011-09-06 | — | — | US | disclosed |
| WO-2009131730-A2 | IMMUNOGENIC COMPOSITIONS FOR ACTIVATING γδ T CELLS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2009-10-29 | — | — | WO | disclosed |
| US-20090196887-A1 | Immunogenic Compositions for Activating Gamma Delta T Cells | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2009-08-06 | — | — | US | disclosed |