Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24010082 | 0.92 | DRD2 (0.34) | DRD2SIGMAR1SMN1; SMN2DRD3DRD1 | |
| SCHEMBL24008888 | 0.83 | SMN1; SMN2 (0.34) | SMN1; SMN2DRD3ADRA2BHRH1 | |
| SCHEMBL178300 | 0.80 | KMT2A (0.44) | DRD2SIGMAR1SMN1; SMN2DRD3ADRA2B | |
| SCHEMBL24837312 | 0.79 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL12854185 | 0.76 | — | — | |
| SCHEMBL24837313 | 0.73 | KDM4E (0.32) | — | |
| SCHEMBL25826575 | 0.73 | PIK3CD (0.44) | SMN1; SMN2 | |
| SCHEMBL24010081 | 0.73 | NPSR1 (0.31) | — | |
| SCHEMBL1046369 | 0.73 | DRD2 (0.52) | DRD2SIGMAR1DRD3GNAI3GNAO1 | |
| SCHEMBL19546253 | 0.73 | DRD2 (0.52) | DRD2SIGMAR1DRD3GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021225969-A1 | IMINO SULFANONE INHIBITORS OF ENPP1 | VOLASTRA THERAPEUTICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |