SCHEMBL2401145

SCHEMBL2401145

CCO[Si](CCCN1CCNCC1)(OCC)OCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 2/20 0.43
DRD2 P14416 1/20 0.38
DRD3 P35462 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
KDM4E B2RXH2 1/20 0.37
NPC1 O15118 1/20 0.37
ALDH1A1 P00352 1/20 0.37
RAB9A P51151 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
POLB P06746 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HSD17B10 Q99714 1/20 0.36
GNAO1 P09471 4/20 0.36
GNAI3 P08754 3/20 0.36
GNAI1 P63096 3/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SOD3 P08294 2/20 0.35
HRH2 P25021 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3358618 0.98 CXCR4 (0.42) CXCR4DRD2DRD3SIGMAR1KDM4E
SCHEMBL7530676 0.98 CXCR4 (0.46) CXCR4DRD2DRD3SIGMAR1KDM4E
SCHEMBL4063582 0.95 CXCR4 (0.44) CXCR4DRD2DRD3SIGMAR1KDM4E
SCHEMBL7526453 0.92 CXCR4 (0.57) CXCR4DRD2DRD3SIGMAR1KDM4E
SCHEMBL7529422 0.92 CXCR4 (0.57) CXCR4DRD2DRD3SIGMAR1KDM4E
SCHEMBL7077208 0.91 CXCR4 (0.60) CXCR4DRD2DRD3SIGMAR1KDM4E
SCHEMBL28432806 0.90 CXCR4 (0.33) CXCR4DRD2DRD3KDM4ENPC1
SCHEMBL4061260 0.89 POLB (0.38) CXCR4DRD2DRD3SIGMAR1KDM4E
SCHEMBL7523904 0.88 CXCR4 (0.51) CXCR4SIGMAR1ALDH1A1GNAO1GNAI3
SCHEMBL11656246 0.88 CXCR4 (0.42) CXCR4SIGMAR1POLBSMN1; SMN2GNAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018122-B2 Method for producing silane-modified polymers MERZ+BENTELI AG (CH) 2024-06-25 US claimed
CN-115340821-B Metal-based high-strength room-temperature-cured phenylamide ester-based silicone protective coating as well as preparation method and application thereof 国科广化精细化工孵化器(南雄)有限公司 2023-06-27 CN claimed
EP-3877438-B1 METHOD FOR THE PREPARATION OF SILANE-MODIFIED POLYMERS MERZ BENTELI AG (CH) 2023-06-14 EP claimed
CN-113166358-B Process for preparing silane-modified polymers 默兹奔特利股份公司 2023-03-28 CN claimed
CN-115340821-A Metal-based high-strength room-temperature-curing phenylamide ester silicon resin protective coating and preparation method and application thereof 国科广化精细化工孵化器(南雄)有限公司 2022-11-15 CN claimed
US-11401379-B2 Oraganocarbonate-modified prepolymer, its use as a reactant for the preparation of isocyanate-free and isothiocyanate-free alkoxysilane polymers, and compositions thereof MERZ+BENTELI AG (CH) 2022-08-02 US claimed
US-20210395450-A1 METHOD FOR PRODUCING SILANE-MODIFIED POLYMERS MERZ+BENTELI AG (CH) 2021-12-23 US claimed
CN-113660922-A Encapsulated compositions 奇华顿股份有限公司 2021-11-16 CN claimed
EP-3877438-A1 METHOD FOR PRODUCING SILANE-MODIFIED POLYMERS merz+benteli ag (CH) 2021-09-15 EP claimed
CN-113166358-A Process for preparing silane-modified polymers 默兹奔特利股份公司 2021-07-23 CN claimed
US-20190352461-A1 USE OF AN ORAGANOCARBONATE-MODIFIED PREPOLYMER AS REACTANT FOR PREPARATION OF ISOCYANATE-FREE AND ISOTHIOCYANATE-FREE ALKOXYSILANE POLYMERS MERZ+BENTELI AG (CH) 2019-11-21 US claimed
EP-3507320-A1 USE OF AN ORGANOCARBONATE-MODIFIED PREPOLYMER AS REACTANT FOR PREPARATION OF ISOCYANATE-FREE AND ISOTHIOCYANATE-FREE ALKOXYSILANE POLYMERS merz+benteli ag (CH) 2019-07-10 EP claimed
CN-109996826-A Purposes of the carbonate-modified prepolymer of organic group as the reactant for being used to prepare the alkoxysilane polymer without isocyanates and without isothiocyanates 默兹奔特利股份公司 2019-07-09 CN claimed
CN-109749085-A A kind of crosslinking silicone type acrylate oligomer and its Photocurable composition of preparation 新丰博兴聚合材料有限公司 2019-05-14 CN claimed
WO-2018042030-A1 USE OF AN ORGANOCARBONATE-MODIFIED PREPOLYMER AS REACTANT FOR PREPARATION OF ISOCYANATE-FREE AND ISOTHIOCYANATE-FREE ALKOXYSILANE POLYMERS MERZ+BENTELI AG (CH) 2018-03-08 WO claimed
CN-103467745-B The preparation method of terminal alkoxy polysiloxane CHENGDU GUIBAO SCIENCE AND TECHNOLOGY INDUSTRIAL CO., LTD. (CN) 2015-08-05 CN claimed
US-7569691-B2 Protected piperazino group-bearing organoxysilane compound and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-08-04 US claimed
EP-0417755-B1 Packing for chromatography and its use for separating water soluble organic compounds DAISO CO LTD (JP) 1993-12-29 EP claimed
US-5103000-A PACKING FOR CHROMATOGRAPHY AND METHOD FOR SEPARATING WATER SOLUBLE ORGANIC COMPOUNDS USING THE SAME DAISO CO., LTD. (JP) 1992-04-07 US claimed
EP-0417755-A1 Packing for chromatography and its use for separating water soluble organic compounds DAISO CO., LTD. (JP) 1991-03-20 EP claimed