Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SOD3 | P08294 | 2/20 | 0.34 |
| ▸ | HRH2 | P25021 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2401145 | 0.98 | CXCR4 (0.43) | CXCR4DRD2DRD3SIGMAR1KDM4E | |
| SCHEMBL7530676 | 0.97 | CXCR4 (0.46) | CXCR4DRD2DRD3SIGMAR1KDM4E | |
| SCHEMBL4063582 | 0.93 | CXCR4 (0.44) | CXCR4DRD2DRD3SIGMAR1KDM4E | |
| SCHEMBL7526453 | 0.91 | CXCR4 (0.57) | CXCR4DRD2DRD3SIGMAR1KDM4E | |
| SCHEMBL7529422 | 0.91 | CXCR4 (0.57) | CXCR4DRD2DRD3SIGMAR1KDM4E | |
| SCHEMBL7077208 | 0.89 | CXCR4 (0.60) | CXCR4DRD2DRD3SIGMAR1KDM4E | |
| SCHEMBL28432806 | 0.88 | CXCR4 (0.33) | CXCR4DRD2DRD3KDM4ENPC1 | |
| SCHEMBL4061260 | 0.87 | POLB (0.38) | CXCR4DRD2DRD3SIGMAR1KDM4E | |
| SCHEMBL7523904 | 0.87 | CXCR4 (0.51) | CXCR4SIGMAR1ALDH1A1GNAI3GNAO1 | |
| SCHEMBL11656246 | 0.86 | CXCR4 (0.42) | CXCR4SIGMAR1POLBSMN1; SMN2GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100010166-A1 | SILANE-TERMINATED PREPOLYMERS AND RELATIVE ADHESIVE SEALANT FORMULATIONS | N.P.T. S.R.L. (IT) | 2010-01-14 | — | — | US | disclosed |
| EP-2064256-A1 | SILANE-TERMINATED PREPOLYMERS AND RELATIVE ADHESIVE SEALANT FORMULATIONS | N.P.T. S.R.L. (IT) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008031895-A1 | SILANE-TERMINATED PREPOLYMERS AND RELATIVE ADHESIVE SEALANT FORMULATIONS | N.P.T. S.R.L. (IT) | 2008-03-20 | — | — | WO | disclosed |