Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24011634 | 0.92 | SMN1; SMN2 (0.61) | NPC1SMN1; SMN2RAB9AALDH1A1POLB | |
| SCHEMBL24011043 | 0.90 | NPC1 (0.65) | NPC1SMN1; SMN2RAB9AALDH1A1POLB | |
| SCHEMBL24011257 | 0.89 | SMN1; SMN2 (0.65) | NPC1SMN1; SMN2RAB9AALDH1A1MAPT | |
| SCHEMBL24011559 | 0.88 | ALDH1A1 (0.62) | NPC1SMN1; SMN2RAB9AALDH1A1POLB | |
| SCHEMBL24011445 | 0.88 | SMN1; SMN2 (0.74) | NPC1SMN1; SMN2RAB9AALDH1A1HPGD | |
| SCHEMBL24011327 | 0.88 | SMN1; SMN2 (0.58) | NPC1SMN1; SMN2RAB9AALDH1A1POLB | |
| SCHEMBL24011345 | 0.87 | NPC1 (0.60) | NPC1SMN1; SMN2RAB9AALDH1A1POLB | |
| SCHEMBL24011474 | 0.87 | SMN1; SMN2 (0.63) | NPC1SMN1; SMN2RAB9AALDH1A1POLB | |
| SCHEMBL26633903 | 0.86 | NPC1 (0.59) | NPC1SMN1; SMN2RAB9AALDH1A1POLB | |
| SCHEMBL24011209 | 0.85 | SMN1; SMN2 (0.74) | NPC1SMN1; SMN2RAB9AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226276-A2 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |