Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26764199 | 0.89 | EPHX1 (0.46) | KMT2AMEN1HTTNPSR1POLB | |
| SCHEMBL26764306 | 0.89 | EPHX1 (0.46) | KMT2AMEN1HTTNPSR1POLB | |
| SCHEMBL26633735 | 0.82 | EPHX2 (0.47) | KMT2AMEN1KDM4EALDH1A1CNR1 | |
| SCHEMBL26764196 | 0.80 | MCHR1 (0.46) | CCR2ALDH1A1KCNH2 | |
| SCHEMBL24011500 | 0.79 | EPHX1 (0.53) | KMT2AMEN1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL24011707 | 0.79 | EPHX1 (0.53) | KMT2AMEN1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL24011708 | 0.79 | EPHX1 (0.53) | KMT2AMEN1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL26764143 | 0.78 | SMN1; SMN2 (0.49) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL26633918 | 0.76 | EPHX1 (0.44) | KMT2AMEN1HTTNPSR1POLB | |
| SCHEMBL26633782 | 0.73 | EPHX1 (0.49) | KMT2AMEN1ALDH1A1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226276-A2 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |