Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24011500 | 1.00 | EPHX1 (0.53) | EPHX1DRD4MCHR1SMN1; SMN2RAB9A | |
| SCHEMBL24011708 | 1.00 | EPHX1 (0.53) | EPHX1DRD4MCHR1SMN1; SMN2RAB9A | |
| SCHEMBL24011394 | 0.90 | MCHR1 (0.52) | EPHX1DRD4MCHR1SMN1; SMN2RAB9A | |
| SCHEMBL26764306 | 0.89 | EPHX1 (0.46) | EPHX1DRD4MCHR1SMN1; SMN2RAB9A | |
| SCHEMBL26764199 | 0.89 | EPHX1 (0.46) | EPHX1DRD4MCHR1SMN1; SMN2RAB9A | |
| SCHEMBL24011390 | 0.89 | SMN1; SMN2 (0.56) | DRD4MCHR1SMN1; SMN2RAB9AHRH3 | |
| SCHEMBL24011373 | 0.87 | EPHX1 (0.51) | EPHX1DRD4MCHR1SMN1; SMN2RAB9A | |
| SCHEMBL24011381 | 0.84 | EPHX1 (0.57) | EPHX1DRD4MCHR1SMN1; SMN2RAB9A | |
| SCHEMBL26633918 | 0.79 | EPHX1 (0.44) | EPHX1DRD4MCHR1SMN1; SMN2RAB9A | |
| SCHEMBL24011709 | 0.79 | KMT2A (0.41) | L3MBTL1MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226276-A2 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |