Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 17/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20634793 | 0.83 | HDAC6 (0.43) | HDAC6HDAC1HDAC8HDAC2HDAC10 | |
| SCHEMBL20635518 | 0.83 | HDAC6 (0.47) | HDAC6HDAC1HDAC8HDAC2HDAC10 | |
| SCHEMBL20605426 | 0.82 | HDAC6 (0.56) | HDAC6HDAC1HDAC8HDAC2HDAC10 | |
| SCHEMBL19162216 | 0.81 | HDAC6 (0.73) | HDAC6HDAC1HDAC8HDAC2HDAC10 | |
| SCHEMBL28464322 | 0.79 | HDAC6 (0.49) | HDAC6HDAC1HDAC8HDAC2HDAC10 | |
| SCHEMBL20635520 | 0.79 | HDAC6 (0.47) | HDAC6HDAC1HDAC8HDAC2HDAC10 | |
| SCHEMBL20628955 | 0.77 | HDAC6 (0.47) | HDAC6HDAC1HDAC8HDAC2HDAC10 | |
| SCHEMBL19162037 | 0.76 | HDAC6 (0.78) | HDAC6HDAC1HDAC8HDAC2HDAC10 | |
| SCHEMBL19138965 | 0.76 | HDAC6 (0.78) | HDAC6HDAC1HDAC8HDAC2HDAC10 | |
| Hydrochloric Acid SCHEMBL20605300 | 0.76 | HDAC6 (0.46) | HDAC6HDAC1HDAC8HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177621-B1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | UNIV REGENSBURG (DE) | 2021-11-10 | — | — | EP | disclosed |