Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 4/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13349548 | 0.83 | CTSK (0.50) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL10800638 | 0.83 | CA1 (0.54) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL3499718 | 0.83 | CA1 (0.54) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL13263255 | 0.82 | CTSK (0.60) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL27918413 | 0.79 | CTSK (0.49) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL28718312 | 0.78 | CTSK (0.46) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL7302316 | 0.76 | CA1 (0.46) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL11018592 | 0.76 | CA1 (0.46) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL5571613 | 0.75 | CTSK (0.51) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL19617925 | 0.75 | CA1 (0.49) | CTSKCA1CA2CA7CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2539389-A1 | AMINE POLYMERS FOR USE AS BILE ACID SEQUESTRANTS | Relypsa, Inc. (US) | 2013-01-02 | — | — | EP | claimed |
| WO-2011106548-A1 | AMINE POLYMERS FOR USE AS BILE ACID SEQUESTRANTS | RELYPSA, INC. (US) | 2011-09-01 | — | — | WO | claimed |
| EP-1819693-A1 | ANTITHROMBOTIC DIAMIDES | ELI LILLY AND COMPANY (US) | 2007-08-22 | — | — | EP | claimed |
| WO-2006057868-A1 | ANTITHROMBOTIC DIAMIDES | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | claimed |
| EP-1819693-A1 | ANTITHROMBOTIC DIAMIDES | ELI LILLY AND COMPANY (US) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006057868-A1 | ANTITHROMBOTIC DIAMIDES | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | disclosed |