SCHEMBL24015397

SCHEMBL24015397

CCNC(C(=O)NC(CCCNC(N)=O)C(=O)C(C)C)C(C)C

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 8/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ C3AR1 Q16581 1/20 0.34
▸ SIRT6 Q8N6T7 1/20 0.33
▸ SIRT1 Q96EB6 1/20 0.33
▸ REN P00797 1/20 0.33
▸ LMNA P02545 1/20 0.32
▸ POLB P06746 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ PRSS1 P07477 1/20 0.32
▸ DPP7 Q9UHL4 1/20 0.31
▸ SIRT5 Q9NXA8 1/20 0.31
▸ MMP3 P08254 1/20 0.31
▸ MMP9 P14780 1/20 0.31
▸ HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19101872 1.00 FURIN (0.36) FURINSMN1; SMN2C3AR1SIRT6SIRT1
SCHEMBL21503822 0.90 NPY4R (0.38) FURINSMN1; SMN2
SCHEMBL13113532 0.89 SIRT6 (0.36) FURINSMN1; SMN2C3AR1SIRT6SIRT1
SCHEMBL2734919 0.89 SIRT6 (0.36) FURINSMN1; SMN2C3AR1SIRT6SIRT1
SCHEMBL18818127 0.89 SIRT6 (0.36) FURINSMN1; SMN2C3AR1SIRT6SIRT1
SCHEMBL19678198 0.88 FURIN (0.36) FURINSMN1; SMN2C3AR1SIRT6SIRT1
SCHEMBL22351933 0.88 FURIN (0.37) FURINSMN1; SMN2C3AR1SIRT6SIRT1
SCHEMBL17758699 0.88 FURIN (0.37) FURINSMN1; SMN2C3AR1SIRT6SIRT1
SCHEMBL19996650 0.88 FURIN (0.37) FURINSMN1; SMN2C3AR1SIRT6SIRT1
SCHEMBL21915057 0.88 C3AR1 (0.34) FURINSMN1; SMN2C3AR1SIRT6SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210346387-A1 ANTIBODY CONJUGATES COMPRISING TOLL-LIKE RECEPTOR AGONIST NOVARTIS AG (CH) 2021-11-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210346387-A1 ANTIBODY CONJUGATES COMPRISING TOLL-LIKE RECEPTOR AGONIST TLR3, TLR2, TLR9 FURIN 3280/4885SMN1; SMN2 3263/4885C3AR1 93/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback