SCHEMBL2401558

SCHEMBL2401558

Cc1cc2c(cc1C)C(C)(C)C1(C=Nc3c(ccc4ccccc34)O1)N2C

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.76
KDM4E B2RXH2 5/20 0.76
THRB P10828 4/20 0.76
SMN1; SMN2 Q16637 4/20 0.76
ALOX12 P18054 2/20 0.76
L3MBTL1 Q9Y468 2/20 0.76
PKM P14618 1/20 0.76
HTT P42858 3/20 0.61
LMNA P02545 3/20 0.61
GAA P10253 3/20 0.61
ALDH1A1 P00352 2/20 0.61
HPGD P15428 2/20 0.61
RECQL P46063 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
MAPK1 P28482 2/20 0.61
POLB P06746 1/20 0.61
NPSR1 Q6W5P4 3/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12438151 0.89 MAPT (0.80) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL4620865 0.88 MAPT (0.78) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL5859725 0.88 MAPT (0.61) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL13839771 0.86 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL80364 0.86 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL29493002 0.86 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL9869228 0.86 MAPT (0.57) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL11062445 0.86 MAPT (0.57) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL2183705 0.86 MAPT (0.78) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL12415225 0.85 MAPT (0.64) MAPTKDM4ETHRBSMN1; SMN2ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7033581-B2 Method of treating hair with heat and a cap which provides a signal regarding treatment UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. (US) 2006-04-25 US claimed
EP-1424918-B1 METHOD OF TREATING HAIR WITH HEAT AND A CAP WHICH PROVIDES A SIGNAL REGARDING TREATMENT UNILEVER PLC (GB) 2005-11-23 EP claimed
US-20050074639-A1 Method of treating hair with heat and a cap which provides a signal regarding treatment UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2005-04-07 US claimed
US-20030059459-A1 Method of treating hair with heat and a cap which provides a signal regarding treatment UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-03-27 US claimed
US-20030030040-A1 Reversibly variable photochromic color composition for articles composed of synthetic resin LUTHERN JOHN JOSEPH (US) 2003-02-13 US claimed
US-10249693-B2 Organic light-emitting display apparatus SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-02 US disclosed
US-20180166513-A1 ORGANIC LIGHT-EMITTING DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-14 US disclosed
US-20150031785-A1 ADHESIVE COMPOSITION AND ADHESIVE SHEET LINTEC CORPORATION (JP) 2015-01-29 US disclosed
US-20140231780-A1 ORGANIC LIGHT-EMITTING DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2014-08-21 US disclosed
US-8729793-B2 Organic light-emitting display apparatus SAMSUNG DISPLAY CO., LTD. (KR) 2014-05-20 US disclosed
US-8508121-B2 Organic light-emitting display apparatus SAMSUNG DISPLAY CO., LTD. (KR) 2013-08-13 US disclosed
US-20110291552-A1 ORGANIC LIGHT-EMITTING DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2011-12-01 US disclosed
US-20020122780-A1 Photochromic hair coloring composition DRAGOCO GERBERDING & CO AG (DE) 2002-09-05 US disclosed
EP-1044978-A2 1-N-alkyl-5'-[(N'-(un)substituted)amido]spiroindolinonaphthoxazines, their preparation, compositions and (co)polymer matrices containing them Corning S.A. (FR) 2000-10-18 EP disclosed
EP-0595424-B1 Composition and procedure for the preparation of organic glasses GREAT LAKES CHEMICAL ITALIA (IT) 1998-05-13 EP disclosed
EP-0476612-B1 Stabilizing mixture for compounds having photochromatic activity GREAT LAKES CHEMICAL ITALIA (IT) 1997-12-03 EP disclosed
US-5599876-A POLYMERIZABLE LIQUID CONSISTS OF POLYMERIZABLE POLY(ALLYL CARBONATE) OF ALIPHATIC OR CYCLO-ALIPHATIC POLYOL, AN ORGANIC PEROXIDE GENERATOR OF FREE-RADICALS, AN ORGANIC DYE OR PHOTOCHROMIC COMPOUND ENICHEM SYNTHESIS S.P.A. (IT) 1997-02-04 US disclosed
US-5431697-A Reversibly variable color patterning composition for synthetic resin articles MATSUI SHIKISO CHEMICAL CO., LTD. (JP) 1995-07-11 US disclosed
EP-0595424-A2 Composition and procedure for the preparation of organic glasses GREAT LAKES CHEMICAL ITALIA S.r.l. (IT) 1994-05-04 EP disclosed
US-5242624-A Stabilizers of cyclic amine such as 1,4-diazabicyclo(2.2.2) octane and quinuclidine and a stearically hindered amine ENICHEM SYNTHESIS S.P.A. (IT) 1993-09-07 US disclosed