SCHEMBL4620865

SCHEMBL4620865

Cc1ccc2c(c1)C(C)(C)C1(C=Nc3c(ccc4ccccc34)O1)N2C

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.78
KDM4E B2RXH2 5/20 0.78
THRB P10828 4/20 0.78
SMN1; SMN2 Q16637 4/20 0.78
ALOX12 P18054 2/20 0.78
L3MBTL1 Q9Y468 2/20 0.78
PKM P14618 1/20 0.78
HTT P42858 3/20 0.63
LMNA P02545 3/20 0.63
GAA P10253 3/20 0.63
ALDH1A1 P00352 2/20 0.63
HPGD P15428 2/20 0.63
RECQL P46063 2/20 0.63
TDP1 Q9NUW8 2/20 0.63
MAPK1 P28482 2/20 0.63
POLB P06746 1/20 0.63
NPSR1 Q6W5P4 3/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12438151 0.93 MAPT (0.80) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL14870331 0.88 MAPT (0.77) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL29493005 0.88 MAPT (0.77) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL3439007 0.88 MAPT (0.77) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL1626757 0.88 MAPT (0.77) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL2401558 0.88 MAPT (0.76) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL80364 0.88 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL13839771 0.88 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL29493002 0.88 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL9868283 0.87 MAPT (0.59) MAPTKDM4ETHRBSMN1; SMN2ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1404768-B1 POLYURETHANE BASED BALLPOINT INKS BIC CORP (US) 2020-04-22 EP disclosed
US-7425406-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2008-09-16 US disclosed
US-7425406-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2008-09-16 US disclosed
EP-1758447-A4 COLOR-CHANGING FISHING EQUIPMENT PURE FISHING INC (US) 2008-06-04 EP disclosed
EP-1311635-B1 SOLVENT-BASED NON-FLUORESCENT INKS FOR WRITING INSTRUMENTS BASED UPON PIGMENT DISPERSIONS IN NON-AQUEOUS SOLVENTS BIC CORP (US) 2008-03-19 EP disclosed
EP-1758447-A2 COLOR-CHANGING FISHING EQUIPMENT Pure Fishing, Inc. (US) 2007-03-07 EP disclosed
WO-2006009606-A2 COLOR-CHANGING FISHING EQUIPMENT PURE FISHING, INC. (US) 2006-01-26 WO disclosed
US-20050274055-A1 Color-changing fishing equipment PURE FISHING, INC. 2005-12-15 US disclosed
EP-1311635-A4 SOLVENT-BASED NON-FLUORESCENT INKS FOR WRITING INSTRUMENTS BASED UPON PIGMENT DISPERSIONS IN NON-AQUEOUS SOLVENTS BIC CORP (US) 2005-02-02 EP disclosed
US-6797748-B2 NON-ERASABLE INK COMPOSITION SUITABLE FOR USE PENS; SMOOTH WRITING PERFORMANCE AND NON-SEEPAGE BIC CORPORATION 2004-09-28 US disclosed
EP-1311635-A1 SOLVENT-BASED NON-FLUORESCENT INKS FOR WRITING INSTRUMENTS BASED UPON PIGMENT DISPERSIONS IN NON-AQUEOUS SOLVENTS BIC CORPORATION (US) 2003-05-21 EP disclosed
US-20030055127-A1 Polyurethane based inks for writing instruments BIC CORPORATION 2003-03-20 US disclosed
US-6503965-B1 Ink composition comprising nonfluorescent pigment predispersed in alkyd resin, high boiling point hydrocarbon solvent, and stabilizer selected from antioxidants and antiskinning agents, which prevents alkyd resin from polymerizing BIC CORPORATION 2003-01-07 US disclosed
WO-2002016516-A1 SOLVENT-BASED NON-FLUORESCENT INKS FOR WRITING INSTRUMENTS BASED UPON PIGMENT DISPERSIONS IN NON-AQUEOUS SOLVENTS BIC CORPORATION (US) 2002-02-28 WO disclosed
EP-0726138-A1 Production process of plastic photochromic lens KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-08-14 EP disclosed
US-5208132-A Microencapsulation of hindered amines MATSUI SHIKISO CHEMICAL CO., LTD. (JP) 1993-05-04 US disclosed
US-4756973-A Three-dimensional network structure layer forming resin containing spirooxazine compound and phenolic resin KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-07-12 US disclosed