Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.51 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17154094 | 0.83 | NPSR1 (0.41) | QPCTQPCTLMTNR1AMTNR1BKDM4E | |
| SCHEMBL24082741 | 0.73 | HCAR2 (0.43) | KDM4EALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL10282891 | 0.70 | — | — | |
| SCHEMBL3696353 | 0.70 | QPCT (0.55) | QPCTQPCTLMTNR1AMTNR1BKDM4E | |
| SCHEMBL4847161 | 0.69 | HCAR2 (0.43) | KDM4EALDH1A1MAPT | |
| SCHEMBL9553014 | 0.69 | SMN1; SMN2 (0.42) | KDM4EALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL16629781 | 0.69 | — | — | |
| SCHEMBL7750984 | 0.69 | HCAR2 (0.35) | LMNA | |
| Hydrochloric Acid SCHEMBL1374074 | 0.68 | ALDH1A1 (0.43) | KDM4EALDH1A1MAPT | |
| SCHEMBL12985517 | 0.68 | HTT (0.48) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072974-A1 | TRICYCLIC HETEROCYCLES | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | WO | disclosed |
| WO-2021224291-A1 | TRICYCLIC HETEROCYCLES USEFUL AS TEAD BINDERS | MERCK PATENT GMBH (DE) | 2021-11-11 | — | — | WO | disclosed |