Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.46 |
| ▸ | FABP7 | O15540 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29616789 | 0.96 | TLR2 (0.47) | KMT2AFABP5FABP7TLR2CASP3 | |
| SCHEMBL28601865 | 0.95 | TLR2 (0.48) | KMT2AFABP5FABP7TLR2CASP3 | |
| SCHEMBL97613 | 0.86 | KMT2A (0.50) | KMT2AFABP5FABP7TLR2CASP3 | |
| SCHEMBL1829604 | 0.86 | FABP5 (0.50) | KMT2AFABP5FABP7CASP3EPHX2 | |
| SCHEMBL1829602 | 0.86 | FABP5 (0.50) | KMT2AFABP5FABP7CASP3EPHX2 | |
| SCHEMBL25144 | 0.85 | KMT2A (0.49) | KMT2AFABP5FABP7TLR2CASP3 | |
| SCHEMBL21029826 | 0.85 | KMT2A (0.45) | KMT2AFABP5FABP7TLR2CASP3 | |
| SCHEMBL3976225 | 0.84 | KMT2A (0.48) | KMT2AFABP5FABP7TLR2CASP3 | |
| SCHEMBL524545 | 0.84 | KMT2A (0.48) | KMT2AFABP5FABP7TLR2CASP3 | |
| SCHEMBL525558 | 0.84 | KMT2A (0.48) | KMT2AFABP5FABP7TLR2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108025071-B | Dual variable domain immunoconjugates and uses thereof | 斯克利普斯研究院 | 2022-11-01 | — | — | CN | disclosed |
| WO-2017205336-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-11-30 | — | — | WO | disclosed |
| EP-2545072-B1 | LIPID-PEPTIDE-POLYMER CONJUGATES AND NANOPARTICLES THEREOF | UNIV CALIFORNIA (US) | 2017-11-22 | — | — | EP | disclosed |
| US-20160009770-A1 | LIPID-PEPTIDE-POLYMER CONJUGATES AND NANOPARTICLES THEREOF | UNITED STATES DEPARTMENT OF ENERGY | 2016-01-14 | — | — | US | disclosed |
| US-9044514-B2 | Lipid-peptide-polymer conjugates and nanoparticles thereof | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-06-02 | — | — | US | disclosed |
| US-20130121917-A1 | Lipid-Peptide-Polymer Conjugates and Nanoparticles Thereof | LAWRENCE BERKELEY NATIONAL LABORATORY (US) | 2013-05-16 | — | — | US | disclosed |
| EP-2545072-A2 | LIPID-PEPTIDE-POLYMER CONJUGATES AND NANOPARTICLES THEREOF | The Regents of the University of California (US) | 2013-01-16 | — | — | EP | disclosed |
| WO-2011112999-A2 | LIPID-PEPTIDE-POLYMER CONJUGATES AND NANOPARTICLES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-09-15 | — | — | WO | disclosed |