SCHEMBL25144

SCHEMBL25144

NCCCCC(C(=O)O)C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.49
FABP5 Q01469 3/20 0.45
FABP7 O15540 2/20 0.45
TLR2 O60603 2/20 0.44
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
EPHX2 P34913 1/20 0.41
MDM4 O15151 1/20 0.40
TP53 P04637 1/20 0.40
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
CASP3 P42574 2/20 0.39
HTR2A P28223 1/20 0.39
MDM2 Q00987 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL525558 0.99 KMT2A (0.48) KMT2AFABP5FABP7TLR2CA1
SCHEMBL524835 0.99 KMT2A (0.48) KMT2AFABP5FABP7TLR2CA1
SCHEMBL28036073 0.99 KMT2A (0.48) KMT2AFABP5FABP7TLR2CA1
SCHEMBL3426738 0.99 KMT2A (0.48) KMT2AFABP5FABP7TLR2CA1
SCHEMBL524545 0.99 KMT2A (0.48) KMT2AFABP5FABP7TLR2CA1
SCHEMBL3976225 0.99 KMT2A (0.48) KMT2AFABP5FABP7TLR2CA1
SCHEMBL97613 0.96 KMT2A (0.50) KMT2AFABP5FABP7TLR2CA1
Succinic Acid SCHEMBL28760118 0.95 KMT2A (0.50) KMT2AFABP5FABP7TLR2CA1
SCHEMBL28463133 0.91 KMT2A (0.48) KMT2AFABP5FABP7TLR2CA1
SCHEMBL14947096 0.91 KMT2A (0.52) KMT2AFABP5FABP7CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 831 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119912519-A Double-target targeted polypeptide compound, preparation method and application 中国人民解放军总医院第一医学中心 2025-05-02 CN claimed
EP-4735047-A1 PEGYLATED LINKERS AND USES THEREOF Université de Tours (FR) 2026-05-06 EP disclosed
EP-4731229-A1 SIRNA, CONJUGATE WHICH CONTAIN SIRNA, PHARMACEUTICAL COMPOSITION AND USES THEREOF Hansoh Bio LLC (US) 2026-04-29 EP disclosed
EP-4729529-A1 PREPARATION OF PEPTIDE INHIBITOR OF INTERLEUKIN-23 RECEPTOR AND USE THEREOF Xizang Haisco Pharmaceutical Co., Ltd. (CN) 2026-04-22 EP disclosed
EP-4712969-A1 CYCLIN INHIBITORS Circle Pharma, Inc. (US) 2026-03-25 EP disclosed
US-12576168-B2 Peptide PET/SPECT probes specific to oncoproteins in tumor extracellular matrix CASE WESTERN RESERVE UNIVERSITY (US) 2026-03-17 US disclosed
EP-3231446-B1 COMPOSITIONS AND METHODS FOR SELECTIVE DELIVERY OF OLIGONUCLEOTIDE MOLECULES TO SPECIFIC NEURON TYPES PALOMO LTD (CY) 2026-01-07 EP disclosed
US-12516145-B2 Bioactive peptide brush polymers via photoinduced reversible-deactivation radical polymerization NORTHWESTERN UNIVERSITY (US) 2026-01-06 US disclosed
US-20260002155-A1 SIRNA THERAPY FOR TRANSTHYRETIN (TTR) RELATED OCULAR AMYLOIDOSIS ALNYLAM PHARMACEUTICALS INC (US) 2026-01-01 US disclosed
US-20250376682-A1 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF TRANSTHYRETIN ALNYLAM PHARMACEUTICALS INC (US) 2025-12-11 US disclosed
US-5726243-A Mild solid-phase synthesis of aligned, branched triple-helical peptides REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1998-03-10 US disclosed
EP-0785941-A1 PORPHYRIN LABELING OF POLYNUCLEOTIDES STRATAGENE (US) 1997-07-30 EP disclosed
WO-1997017984-A1 OLIGODENDROCYTE-SPECIFIC PROTEIN AND METHOD FOR TREATING DISEASE RESEARCH GENETICS, INC. (US) 1997-05-22 WO disclosed
US-5591646-A Method and apparatus for peptide synthesis and screening ARRIS PHARMACEUTICAL (US) 1997-01-07 US disclosed
US-5585275-A Pilot apparatus for peptide synthesis and screening ARRIS PHARMACEUTICAL CORPORATION (US) 1996-12-17 US disclosed
US-5576419-A Mild solid-phase synthesis of aligned branched triple-helical peptides REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1996-11-19 US disclosed
WO-1996011937-A1 PORPHYRIN LABELING OF POLYNUCLEOTIDES STRATAGENE (US) 1996-04-25 WO disclosed
WO-1994005394-A1 SPECIFICATION METHOD AND APPARATUS FOR PEPTIDE SYNTHESIS AND SCREENING ARRIS PHARMACEUTICAL CORPORATION (US) 1994-03-17 WO disclosed
EP-0541663-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS HAVING GLYCOPROTEIN HORMONE AGONISTIC OR ANTAGONISTIC ACTIVITY STICHTING CENTRAAL DIERGENEESKUNDIG INSTITUUT (NL) 1993-05-19 EP disclosed
WO-1992002542-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS HAVING GLYCOPROTEIN HORMONE AGONISTIC OR ANTAGONISTIC ACTIVITY STICHTING CENTRAAL DIERGENEESKUNDIG INSTITUUT (NL) 1992-02-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12576168-B2 Peptide PET/SPECT probes specific to oncoproteins in tumor extracellular matrix FN1, INHA, EDNRB KMT2A 1886/4885FABP5 814/4885FABP7 343/4885
US-20250376682-A1 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF TRANSTHYRETIN TTR, RNGTT, RNASE1 KMT2A 3210/4885FABP5 223/4885FABP7 369/4885
US-20260002155-A1 SIRNA THERAPY FOR TRANSTHYRETIN (TTR) RELATED OCULAR AMYLOIDOSIS TTR, APOB, APOL1 KMT2A 3305/4885FABP5 748/4885FABP7 671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.