SCHEMBL24017002

SCHEMBL24017002

COC(=O)c1ccc(C(N)C(N)c2ccc(C(=O)OC)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.57
CA2 P00918 4/20 0.57
CA12 O43570 3/20 0.57
CA9 Q16790 3/20 0.57
CA14 Q9ULX7 3/20 0.57
TDP1 Q9NUW8 1/20 0.57
CA7 P43166 1/20 0.57
MAPT P10636 6/20 0.57
LOXL2 Q9Y4K0 1/20 0.55
TSHR P16473 1/20 0.54
DPP4 P27487 2/20 0.53
ALDH1A1 P00352 2/20 0.52
STS P08842 1/20 0.50
RAB9A P51151 3/20 0.49
NPC1 O15118 1/20 0.49
GAA P10253 2/20 0.49
KDM4E B2RXH2 2/20 0.49
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
GLA P06280 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24017001 1.00 CA1 (0.57) CA1CA2CA12CA9CA14
Hydrochloric Acid SCHEMBL30098269 0.98 CA1 (0.55) CA1CA2CA12CA9CA14
SCHEMBL10154464 0.90 CA1 (0.52) CA1CA2CA12CA9CA14
SCHEMBL14551916 0.90 CA1 (0.52) CA1CA2CA12CA9CA14
SCHEMBL14551218 0.90 CA1 (0.52) CA1CA2CA12CA9CA14
SCHEMBL6011750 0.88 CA1 (0.57) CA1CA2CA12CA9CA14
SCHEMBL881385 0.86 CA1 (0.55) CA1CA2CA12CA9CA14
SCHEMBL942575 0.86 CA1 (0.55) CA1CA2CA12CA9CA14
SCHEMBL2294346 0.86 CA1 (0.55) CA1CA2CA12CA9CA14
Hydrochloric Acid SCHEMBL1725229 0.84 CA1 (0.53) CA1CA2CA12CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021223156-A1 DIBORON GLYCOL ESTER, PREPARATION METHOD THEREFOR, INTERMEDIATE THEREOF, AND APPLICATION THEREOF 中国科学院上海有机化学研究所 2021-11-11 WO disclosed