SCHEMBL942575

SCHEMBL942575

COC(=O)c1ccc(C(C)N)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.55
CA2 P00918 4/20 0.55
CA12 O43570 3/20 0.55
CA9 Q16790 3/20 0.55
CA14 Q9ULX7 3/20 0.55
TDP1 Q9NUW8 1/20 0.55
CA7 P43166 1/20 0.55
MAPT P10636 4/20 0.55
LOXL2 Q9Y4K0 1/20 0.53
TSHR P16473 1/20 0.52
DPP4 P27487 2/20 0.51
RAB9A P51151 2/20 0.51
NPC1 O15118 1/20 0.51
ROCK2 O75116 2/20 0.50
ROCK1 Q13464 2/20 0.50
ALDH1A1 P00352 1/20 0.50
STS P08842 1/20 0.49
GAA P10253 1/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2294346 1.00 CA1 (0.55) CA1CA2CA12CA9CA14
SCHEMBL881385 1.00 CA1 (0.55) CA1CA2CA12CA9CA14
Hydrochloric Acid SCHEMBL1725229 0.98 CA1 (0.53) CA1CA2CA12CA9CA14
Hydrochloric Acid SCHEMBL871925 0.98 CA1 (0.53) CA1CA2CA12CA9CA14
Hydrochloric Acid SCHEMBL872093 0.98 CA1 (0.53) CA1CA2CA12CA9CA14
Sulfuric Acid SCHEMBL3915312 0.93 CA1 (0.52) CA1CA2CA12CA9CA14
Sulfuric Acid SCHEMBL2296056 0.93 CA1 (0.52) CA1CA2CA12CA9CA14
Sulfuric Acid SCHEMBL2296055 0.93 CA1 (0.52) CA1CA2CA12CA9CA14
SCHEMBL24017001 0.86 CA1 (0.57) CA1CA2CA12CA9CA14
SCHEMBL24017002 0.86 CA1 (0.57) CA1CA2CA12CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504437-A Method for denitrification alkylation of aromatic methylamine 中国科学技术大学 2025-02-25 CN claimed
CN-109415553-B Plasticized thermoset resins and related cured resins, curing methods, and articles comprising cured resins 马萨诸塞大学 2022-08-05 CN claimed
EP-3481899-A1 PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN The University of Massachusetts (US) 2019-05-15 EP claimed
CN-109415553-A The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin 马萨诸塞大学 2019-03-01 CN claimed
WO-2018008003-A1 PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN THE UNIVERSITY OF MASSACHUSETTS (US) 2018-01-11 WO claimed
US-8008062-B2 Production of (R)- and (S)-4-(1-aminoethyl) benzoic acid methyl ester sulfate by lipase acylation of racemic 4-(1-aminoethyl) benzoic acid methyl ester and sulfuric acid precipitation BASF SE (DE) 2011-08-30 US claimed
EP-1969129-B1 PROCESS FOR THE PREPARATION OF (R)- AND (S)-4-(1-AMINOMETHYL) BENZOIC ACID METHYLESTER-SULPHATE FROM RACEMIC 4-(1-AMINOETHYL)BENZOIC ACID METHYLESTER BASF SE (DE) 2009-03-11 EP claimed
US-20080305530-A1 Method for Producing (R)-and (S)-4-(1-Ammoniumethyl)Benzoic Acid Methylester-Sulphate from Racemic 4-(1-Aminoethyl)Benzoic Acid Methylester by Lipase Catalysed Enantoselective Acylation and Subsequent Precipitation with Sulphuric Acid BASF SE (DE) 2008-12-11 US claimed
CN-101321875-A Method for preparing -and (S) -methyl 4- (1-ammonioethyl) benzoate sulfate from racemic methyl 4- (1-aminoethyl) benzoate by lipase-catalyzed enantioselective acylation and subsequent precipitation with sulfuric acid BASF AG (DE) 2008-12-10 CN claimed
US-20260132147-A1 BAX INHIBITORS AND USES THEREOF CASE WESTERN RESERVE UNIV (US) 2026-05-14 US disclosed
US-12479857-B2 Bax inhibitors and uses thereof CASE WESTERN RESERVE UNIVERSITY (US) 2025-11-25 US disclosed
US-20250179017-A1 CARBOXAMIDE COMPOUNDS AS PGE2 RECEPTOR ANTAGONISTS GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) 2025-06-05 US disclosed
CN-119504437-A Method for denitrification alkylation of aromatic methylamine 中国科学技术大学 2025-02-25 CN disclosed
US-20250051285-A1 CRYSTALLINE SALT FORM OF EP4 ANTAGONIST EISAI R&D MANAGEMENT CO., LTD. (JP) 2025-02-13 US disclosed
CN-1281438-A Piperazine compounds and their use as pharmaceuticals EFUKU CO LTD (JP) 2001-01-24 CN disclosed
US-4753962-A HYPOGLYCEMIC, ANTIOBESITY AGENT BEECHAM GROUP P.L.C. (GB) 1988-06-28 US disclosed
US-4654371-A ANTI-OBESITY, HYPOGLYCEMIA AGENTS BEECHAM GROUP P.L.C. (GB) 1987-03-31 US disclosed
US-4478849-A HYPERGLYCEMIC AGENTS BEECHAM GROUP LIMITED (GB) 1984-10-23 US disclosed
EP-0006735-B1 SECONDARY AMINES, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE BEECHAM GROUP PLC (GB) 1983-06-15 EP disclosed
EP-0006735-A1 Secondary amines, their preparation, pharmaceutical compositions containing them and their use BEECHAM GROUP PLC (GB) 1980-01-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132147-A1 BAX INHIBITORS AND USES THEREOF BAX, BCL2, BAK1 CA1 349/4885CA2 173/4885CA12 2440/4885
US-20250179017-A1 CARBOXAMIDE COMPOUNDS AS PGE2 RECEPTOR ANTAGONISTS PTGER1, PTGER2, CNR2 CA1 1483/4885CA2 430/4885CA12 2186/4885
US-20080305530-A1 Method for Producing (R)-and (S)-4-(1-Ammoniumethyl)Benzoic Acid Methylester-Sulphate from Racemic 4-(1-Aminoethyl)Benzoic Acid Methylester by Lipase Catalysed Enantoselective Acylation and Subsequent Precipitation with Sulphuric Acid ARSA, APEH, STS CA1 1615/4885CA2 1684/4885CA12 2361/4885
US-20250051285-A1 CRYSTALLINE SALT FORM OF EP4 ANTAGONIST PTGER4, FFAR4, EPB41 CA1 136/4885CA2 118/4885CA12 1557/4885
US-12479857-B2 Bax inhibitors and uses thereof BAX, TMBIM6, BCL2 CA1 1738/4885CA2 2862/4885CA12 3943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.