SCHEMBL24017016

SCHEMBL24017016

C=CCCC[C@H](N)[C@@H](N)CCCC=C

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
ALDH1A1 P00352 3/20 0.41
TRPA1 O75762 3/20 0.32
ABCC4 O15439 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24017013 1.00 TSHR (0.41) TSHRALDH1A1TRPA1ABCC4MAPT
SCHEMBL731551 0.85 TSHR (0.40) TSHRALDH1A1
SCHEMBL11147087 0.85 TSHR (0.35) TSHRALDH1A1
SCHEMBL432274 0.82
SCHEMBL1242583 0.82 TSHR (0.41) TSHRALDH1A1TRPA1ABCC4MAPT
SCHEMBL24017136 0.81 TSHR (0.35) TSHRALDH1A1
SCHEMBL24017041 0.81 TSHR (0.35) TSHRALDH1A1
SCHEMBL3241748 0.81 TSHR (0.39) TSHRALDH1A1TRPA1ABCC4MAPT
SCHEMBL3241595 0.81 TSHR (0.39) TSHRALDH1A1TRPA1ABCC4MAPT
SCHEMBL9349243 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021223156-A1 DIBORON GLYCOL ESTER, PREPARATION METHOD THEREFOR, INTERMEDIATE THEREOF, AND APPLICATION THEREOF 中国科学院上海有机化学研究所 2021-11-11 WO disclosed