SCHEMBL1242583

SCHEMBL1242583

C=CCCCC(N)CCCC=C

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
ALDH1A1 P00352 3/20 0.41
TRPA1 O75762 3/20 0.32
ABCC4 O15439 1/20 0.32
MAPT P10636 1/20 0.32
ENPEP Q07075 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1240084 0.92 TSHR (0.42) TSHRALDH1A1TRPA1ABCC4MAPT
SCHEMBL4228975 0.89 TSHR (0.46) TSHRALDH1A1TRPA1ABCC4MAPT
SCHEMBL28719109 0.88 TSHR (0.56) TSHRALDH1A1
SCHEMBL617879 0.88 TSHR (0.50) TSHRALDH1A1
SCHEMBL3244928 0.87
SCHEMBL22651490 0.87 ALDH1A1 (0.36) TSHRALDH1A1ABCC4MAPT
SCHEMBL3996665 0.87 TSHR (0.39) TSHRALDH1A1TRPA1ABCC4MAPT
SCHEMBL274405 0.85
SCHEMBL5596749 0.84 TSHR (0.60) TSHRALDH1A1
SCHEMBL18463150 0.83 TSHR (0.36) TSHRALDH1A1TRPA1ABCC4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3519474-B1 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING DOW GLOBAL TECHNOLOGIES LLC (US) 2024-09-25 EP disclosed
EP-4435013-A2 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING Dow Global Technologies LLC (US) 2024-09-25 EP disclosed
CN-118324715-A Compounds, compositions, and methods of use thereof 艾勒维生技公司 2024-07-12 CN disclosed
EP-3519456-B1 CAPPED MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2024-07-03 EP disclosed
EP-3732211-B1 CAPPED DUAL-HEADED ORGANOALUMINUM COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-05-22 EP disclosed
CN-117750962-A Compounds, compositions, and methods of use thereof 艾勒维生技公司 2024-03-22 CN disclosed
US-11613600-B2 Capped dual-headed organoaluminum compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2023-03-28 US disclosed
US-11492450-B2 Dual-headed organoaluminum compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2022-11-08 US disclosed
US-11359035-B2 Multi- or dual-headed compositions useful for chain shuttling and process to prepare the same DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-14 US disclosed
US-11359038-B2 Capped multi- or dual-headed compositions useful for chain shuttling and process to prepare the same DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-14 US disclosed
EP-3519474-A1 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING Dow Global Technologies LLC (US) 2019-08-07 EP disclosed
EP-3489264-A1 CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS Dow Global Technologies Llc (US) 2019-05-29 EP disclosed
WO-2018064546-A1 CAPPED MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2018-04-05 WO disclosed
WO-2018064540-A1 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING DOW GLOBAL TECHNOLOGIES LLC (US) 2018-04-05 WO disclosed
EP-3243846-A2 MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS Dow Global Technologies Llc (US) 2017-11-15 EP disclosed
EP-2459598-B1 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-10-18 EP disclosed
US-8501885-B2 Dual- or multi-headed chain shuttling agents and their use for preparation of block copolymers DOW GLOBAL TECHNOLOGIES, LLC (US) 2013-08-06 US disclosed
US-20120165486-A1 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR PREPARATION OF BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-06-28 US disclosed
EP-2459598-A2 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS Dow Global Technologies LLC (US) 2012-06-06 EP disclosed
WO-2011016991-A2 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES INC. (US) 2011-02-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11613600-B2 Capped dual-headed organoaluminum compositions CAPG, C5, CDS2 TSHR 4645/4885ALDH1A1 2097/4885TRPA1 146/4885
US-20120165486-A1 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR PREPARATION OF BLOCK COPOLYMERS MSN, COASY, MCM7 TSHR 4812/4885ALDH1A1 3614/4885TRPA1 3958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.