SCHEMBL24017147

SCHEMBL24017147

Cc1ccc([C@@H](N)[C@H](N)c2ccc(C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.50
DPP4 P27487 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
CHRNA7 P36544 1/20 0.48
ALOX5 P09917 1/20 0.40
CA7 P43166 3/20 0.39
MAOA P21397 2/20 0.39
MAOB P27338 1/20 0.39
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
CYP19A1 P11511 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP2A6 P11509 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
CA12 O43570 1/20 0.36
CA3 P07451 1/20 0.36
CA6 P23280 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3258924 1.00 ACHE (0.50) ACHEDPP4TDP1CHRNA7ALOX5
SCHEMBL12569051 1.00 ACHE (0.50) ACHEDPP4TDP1CHRNA7ALOX5
SCHEMBL3253749 1.00 ACHE (0.50) ACHEDPP4TDP1CHRNA7ALOX5
Hydrochloric Acid SCHEMBL30098282 0.97 DPP4 (0.48) ACHEDPP4TDP1CHRNA7ALOX5
Hydrochloric Acid SCHEMBL17137911 0.97 DPP4 (0.48) ACHEDPP4TDP1CHRNA7ALOX5
SCHEMBL18925493 0.87 ACHE (0.62) ACHEDPP4TDP1CHRNA7ALDH1A1
SCHEMBL11085901 0.86 CHRNA7 (0.42) ACHEDPP4TDP1CHRNA7ALOX5
SCHEMBL16232115 0.86 CHRNA7 (0.42) ACHEDPP4TDP1CHRNA7ALOX5
SCHEMBL16232132 0.86 CHRNA7 (0.42) ACHEDPP4TDP1CHRNA7ALOX5
SCHEMBL16232131 0.86 CHRNA7 (0.42) ACHEDPP4TDP1CHRNA7ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111440205-B Biboric acid diol ester, preparation method thereof, intermediate thereof and application thereof 中国科学院上海有机化学研究所 2022-10-04 CN disclosed
WO-2021223156-A1 DIBORON GLYCOL ESTER, PREPARATION METHOD THEREFOR, INTERMEDIATE THEREOF, AND APPLICATION THEREOF 中国科学院上海有机化学研究所 2021-11-11 WO disclosed