Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.77 |
| ▸ | HTT | P42858 | 2/20 | 0.77 |
| ▸ | USP2 | O75604 | 6/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | XBP1 | P17861 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | CYBB | P04839 | 3/20 | 0.60 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.60 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.60 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.60 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15658933 | 0.90 | MAPT (0.84) | MAPTMAPK1HTTUSP2MEN1 | |
| SCHEMBL15662302 | 0.89 | MAPT (0.80) | MAPTMAPK1HTTUSP2MEN1 | |
| SCHEMBL15660651 | 0.82 | MAPT (0.77) | MAPTMAPK1HTTUSP2MEN1 | |
| SCHEMBL21530412 | 0.79 | ALDH1A1 (0.80) | MAPTMAPK1HTTUSP2ALDH1A1 | |
| SCHEMBL21530475 | 0.76 | MAPT (0.85) | MAPTMAPK1HTTUSP2MEN1 | |
| SCHEMBL30100838 | 0.75 | CYBB (1.00) | MAPTMAPK1HTTUSP2MEN1 | |
| SCHEMBL17999762 | 0.75 | CYBB (1.00) | MAPTMAPK1HTTUSP2MEN1 | |
| SCHEMBL24019197 | 0.75 | MAPT (0.77) | MAPTMAPK1HTTUSP2MEN1 | |
| SCHEMBL17999847 | 0.75 | CYBB (1.00) | MAPTMAPK1HTTUSP2MEN1 | |
| SCHEMBL21530421 | 0.75 | SMN1; SMN2 (1.00) | MAPTMAPK1HTTUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11174242-B2 | Heteroaryl compounds and their use | MINORYX THERAPEUTICS S.L. (ES) | 2021-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11174242-B2 | Heteroaryl compounds and their use | GBA1, GBA2, GAA | MAPT 229/4885MAPK1 4688/4885HTT 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.