Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 5/20 | 0.55 |
| ▸ | ALPL | P05186 | 4/20 | 0.55 |
| ▸ | ALPG | P10696 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 3/20 | 0.55 |
| ▸ | JAK2 | O60674 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21952095 | 0.89 | MAPT (0.64) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL27303528 | 0.84 | ALPG (0.78) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL30620388 | 0.84 | ALPG (0.78) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL21951986 | 0.79 | MAPT (0.71) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL24209668 | 0.78 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL30296082 | 0.77 | CPB1 (0.50) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL21952054 | 0.76 | MAPT (0.64) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL24209657 | 0.76 | MAPT (0.82) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL29509840 | 0.76 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL24209682 | 0.76 | MAPT (0.71) | MAPTALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3909577-A1 | UBIQUITIN-LIGASE INHIBITORS FOR THE TREATMENT OF CANCER | Fundación Profesor Novoa Santos (ES) | 2021-11-17 | — | — | EP | disclosed |