SCHEMBL24022103

SCHEMBL24022103

CCn1c2cc(Sc3ccccc3)ccc2c2ccc(N(c3ccccc3)c3ccc4c(c3)C3(c5cc(N(c6ccccc6)c6ccc7c8ccc(Sc9ccccc9)cc8n(CC)c7c6)ccc5-4)c4cc(N(c5ccccc5)c5ccc6c7ccc(Sc8ccccc8)cc7n(CC)c6c5)ccc4-c4ccc(N(c5ccccc5)c5ccc6c7ccc(Sc8ccccc8)cc7n(CC)c6c5)cc43)cc21

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 1/20 0.37
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
CNR1 P21554 9/20 0.34
CNR2 P34972 8/20 0.34
KDM1A O60341 1/20 0.32
METAP2 P50579 4/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30
HBB P68871 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21939986 0.97 CSF1R (0.35) CSF1RMAOAMAOBCNR1CNR2
SCHEMBL21939882 0.92 CSF1R (0.33) CSF1RMAOAMAOBCNR1CNR2
SCHEMBL24022101 0.92 HTR2C (0.35) CSF1RMAOAMAOBCNR1CNR2
SCHEMBL21939884 0.91 MAOA (0.33) CSF1RMAOAMAOBCNR1CNR2
SCHEMBL21939868 0.91 KDM1A (0.33) KDM1AMETAP2KDM4EMEN1ALDH1A1
SCHEMBL21939989 0.89 HTR2C (0.34) CSF1RMAOAMAOBCNR1CNR2
SCHEMBL24022100 0.89 KDM4E (0.35) CSF1RMAOAMAOBCNR1CNR2
SCHEMBL21939977 0.88 PDK2 (0.33) KDM1AMETAP2
SCHEMBL21940170 0.87 KDM1A (0.42) KDM1AKDM4EMEN1ALDH1A1MAPT
SCHEMBL21939983 0.86 MAPT (0.33) CSF1RMAOAMAOBCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11177403-B2 Perovskite solar cell KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2021-11-16 US disclosed