SCHEMBL24022113

SCHEMBL24022113

CCn1c2cc(C)ccc2c2ccc(N(c3ccc(OC)cc3)c3ccc4c(c3)C3(c5cc(N(c6ccc(OC)cc6)c6ccc7c8ccc(C)cc8n(CC)c7c6)ccc5-4)c4ccsc4-c4sccc43)cc21

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.34
GRIK1 P39086 1/20 0.31
GRIK2 Q13002 1/20 0.31
METAP2 P50579 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24022279 0.91 DYRK1A (0.39) DYRK1AGRIK1GRIK2METAP2
SCHEMBL21940561 0.91 KDM4E (0.38) GRIK2
SCHEMBL21939873 0.91 GRIK2 (0.35) GRIK1GRIK2
SCHEMBL21940565 0.90 QPCT (0.32) DYRK1AMETAP2
SCHEMBL24022112 0.90
SCHEMBL21940557 0.89 DYRK1A (0.36) DYRK1AGRIK1GRIK2METAP2
SCHEMBL21939872 0.88
SCHEMBL21940541 0.88 METAP2 (0.36) GRIK1GRIK2METAP2
SCHEMBL21939617 0.88 METAP2 (0.34) DYRK1AGRIK2METAP2
SCHEMBL24022126 0.87 DYRK1A (0.36) DYRK1AGRIK1GRIK2METAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11177403-B2 Perovskite solar cell KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2021-11-16 US disclosed