⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4901447 | 0.72 | — | — | |
| SCHEMBL11608955 | 0.68 | — | — | |
| SCHEMBL907804 | 0.67 | — | — | |
| SCHEMBL1162544 | 0.67 | — | — | |
| SCHEMBL31189297 | 0.67 | — | — | |
| Ethanesulfonic Acid Amide SCHEMBL28038 | 0.67 | — | — | |
| SCHEMBL5115519 | 0.67 | — | — | |
| SCHEMBL300230 | 0.67 | — | — | |
| SCHEMBL1644673 | 0.67 | CA2 (0.46) | — | |
| SCHEMBL6200028 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8084613-B2 | Tetrazoyloxime derivative and plant disease control agent | NIPPON SODA CO., LTD. (JP) | 2011-12-27 | — | — | US | claimed |
| US-20220380370-A1 | XANTHINE CB1 INHIBITORS | GFB (ABC), LLC | 2022-12-01 | — | — | US | disclosed |
| EP-4034101-A1 | XANTHINE CB1 INHIBITORS | Goldfinch Bio, Inc. (US) | 2022-08-03 | — | — | EP | disclosed |
| CN-114727983-A | Xanthine CB1 inhibitors | 金翅雀生物公司 | 2022-07-08 | — | — | CN | disclosed |
| WO-2021083438-A1 | INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE - SYNTHESIS AND USE THEREOF FOR TREATMENT OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA AND LYMPHOMA | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) | 2021-05-06 | — | — | WO | disclosed |
| WO-2021083438-A1 | INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE - SYNTHESIS AND USE THEREOF FOR TREATMENT OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA AND LYMPHOMA | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) | 2021-05-06 | — | — | WO | disclosed |
| WO-2021062089-A1 | XANTHINE CB1 INHIBITORS | GOLDFINCH BIO, INC. (US) | 2021-04-01 | — | — | WO | disclosed |
| US-10647725-B2 | Anti-infective 2-aminothiophenes | THE UNIVERSITY OF TOLEDO (US) | 2020-05-12 | — | — | US | disclosed |
| CN-107205396-B | Pesticide composition | 日本曹达株式会社 | 2019-08-30 | — | — | CN | disclosed |
| US-20190119296-A1 | Anti-Infective 2-Aminothiophenes | THE UNIVERSITY OF TOLEDO (US) | 2019-04-25 | — | — | US | disclosed |
| CN-1202168-A | Quinolein-2(1H)-one derivatives as serotonin antagonists | SYNTHELABO (FR) | 1998-12-16 | — | — | CN | disclosed |
| WO-1998042712-A1 | QUINOLINE-2(1H)-ONE AND DIHYDROQUINOLINE-2(1H)-ONE DERIVATIVES AS LIGANDS OF 5-HT, 5-HT2 AND 5-HT1-LIKE RECEPTORS | SANOFI-SYNTHELABO (FR) | 1998-10-01 | — | — | WO | disclosed |
| EP-0850235-A1 | QUINOLEIN-2(1H)-ONE DERIVATIVES AS SEROTONIN ANTAGONISTS | SYNTHELABO (FR) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997010238-A1 | QUINOLEIN-2(1H)-ONE DERIVATIVES AS SEROTONIN ANTAGONISTS | SYNTHELABO (FR) | 1997-03-20 | — | — | WO | disclosed |
| EP-0252640-B1 | ALKANESULFONAMIDES AS ANTIGLAUCOMA AGENTS | MERCK & CO. INC. (US) | 1991-03-06 | — | — | EP | disclosed |
| US-4968809-A | Spirofluoreneisothiazolidinone dioxides as aldose reductase inhibitors | NESTLE S.A. A COMPANY OF SWITZERLAND (CH) | 1990-11-06 | — | — | US | disclosed |
| US-4812463-A | CARBONIC ANHYDRASE INHIBITORS | MERCK & CO., INC. (US) | 1989-03-14 | — | — | US | disclosed |
| EP-0252640-A1 | Alkanesulfonamides as antiglaucoma agents | MERCK & CO. INC. (US) | 1988-01-13 | — | — | EP | disclosed |
| EP-0129478-A2 | 2-Sulfamoylbenzo (b) thiophene derivatives, their preparation and pharmaceutical composition for the treatment of elevated intraocular pressure | MERCK & CO. INC. (US) | 1984-12-27 | — | — | EP | disclosed |
| US-4068000-A | N-TETRACHLOROETHYL-THIO-SUBSTITUTED HALOMETHANESULFONAMIDES, OVICIDES | CHEVRON RESEARCH COMPANY (US) | 1978-01-10 | — | — | US | disclosed |