Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 20/20 | 0.80 |
| ▸ | CDK6 | Q00534 | 19/20 | 0.80 |
| ▸ | CSF1R | P07333 | 13/20 | 0.80 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.67 |
| ▸ | CDK2 | P24941 | 3/20 | 0.67 |
| ▸ | CCNK | O75909 | 2/20 | 0.67 |
| ▸ | CDK7 | P50613 | 2/20 | 0.67 |
| ▸ | CDK9 | P50750 | 2/20 | 0.67 |
| ▸ | CCNH | P51946 | 2/20 | 0.67 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.67 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.67 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.66 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21245628 | 0.89 | CDK4 (1.00) | CDK4CDK6CSF1RCCNA2CDK2 | |
| SCHEMBL21245578 | 0.88 | CDK4 (0.84) | CDK4CDK6CSF1RCCNA2CDK2 | |
| SCHEMBL21267316 | 0.87 | CDK4 (0.89) | CDK4CDK6CSF1RCCNA2CDK2 | |
| SCHEMBL21245760 | 0.87 | CDK4 (0.85) | CDK4CDK6CSF1RCCNA2CDK2 | |
| Hydrochloric Acid SCHEMBL21245632 | 0.87 | CDK4 (0.83) | CDK4CDK6CSF1RCCNA2CDK2 | |
| SCHEMBL21245723 | 0.87 | CDK6 (1.00) | CDK4CDK6CSF1RCCNA2CDK2 | |
| SCHEMBL21245771 | 0.87 | CDK4 (0.85) | CDK4CDK6CSF1RCCNA2CDK2 | |
| SCHEMBL21245810 | 0.86 | CDK4 (1.00) | CDK4CDK6CSF1RCCNA2CDK2 | |
| SCHEMBL21245558 | 0.86 | CDK4 (1.00) | CDK4CDK6CSF1RCCNA2CDK2 | |
| Hydrochloric Acid SCHEMBL21245651 | 0.86 | CDK4 (0.84) | CDK4CDK6CSF1RCCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11174252-B2 | Heterocyclic compounds as kinase inhibitors | NUVATION BIO INC. (US) | 2021-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11174252-B2 | Heterocyclic compounds as kinase inhibitors | CDK6, CDK4, CDK9 | CDK4 2/4885CDK6 1/4885CSF1R 3721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.