Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22044266 | 0.81 | MAPT (0.41) | ALDH1A1CYP3A4KMT2AKDM4ELMNA | |
| SCHEMBL21994273 | 0.81 | S1PR1 (0.42) | CYP3A4KMT2AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL14951063 | 0.76 | ACHE (0.50) | ACHEALDH1A1CYP3A4KMT2AKDM4E | |
| SCHEMBL8379921 | 0.72 | KMT2A (0.49) | ACHEALDH1A1CYP3A4KMT2AKDM4E | |
| SCHEMBL24022773 | 0.71 | MAPT (0.55) | ACHEALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL14951245 | 0.71 | ACHE (0.44) | ACHEALDH1A1CYP3A4KMT2AKDM4E | |
| SCHEMBL16787398 | 0.71 | ACHE (0.44) | ACHEALDH1A1CYP3A4KMT2AKDM4E | |
| SCHEMBL14446041 | 0.71 | ACHE (0.58) | ACHEALDH1A1CYP3A4KDM4ELMNA | |
| SCHEMBL3857605 | 0.71 | ACHE (0.58) | ACHEALDH1A1CYP3A4KMT2AKDM4E | |
| SCHEMBL1505391 | 0.70 | GRM5 (0.42) | ACHEALDH1A1CYP3A4KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021228992-A1 | NUCLIDE LABELLED H-TETRAZINES AND USE THEREOF FOR PET AND SPECT PRETARGETED IMAGING AND RADIONUCLIDE THERAPY | RIGSHOSPITALET (DK) | 2021-11-18 | — | — | WO | disclosed |
| EP-3909944-A1 | NUCLIDE LABELLED H-TETRAZINES AND USE THEREOF FOR PET AND SPECT PRETARGETED IMAGING AND RADIONUCLIDE THERAPY | Rigshospitalet (DK) | 2021-11-17 | — | — | EP | disclosed |