⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20052681 | 0.93 | — | — | |
| SCHEMBL24115625 | 0.82 | SIGMAR1 (0.30) | — | |
| SCHEMBL23945480 | 0.81 | HTR2A (0.30) | — | |
| SCHEMBL20365840 | 0.79 | — | — | |
| SCHEMBL22861708 | 0.79 | — | — | |
| SCHEMBL26406331 | 0.79 | — | — | |
| SCHEMBL24555875 | 0.79 | — | — | |
| SCHEMBL25110612 | 0.79 | — | — | |
| SCHEMBL26997800 | 0.77 | PAOX (0.47) | — | |
| SCHEMBL25793792 | 0.77 | PAOX (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203083-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-06-29 | — | — | US | disclosed |
| US-20230028359-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-01-26 | — | — | US | disclosed |
| US-11174281-B1 | Modified nucleotides and uses thereof | Singular Genomics Systems, Inc. (US) | 2021-11-16 | — | — | US | disclosed |