Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10963241 | 0.87 | SIGMAR1 (0.56) | MAPTRXFP1SIGMAR1CA2MAOA | |
| SCHEMBL8082718 | 0.87 | SIGMAR1 (0.56) | MAPTRXFP1SIGMAR1CA2MAOA | |
| SCHEMBL2792349 | 0.87 | SIGMAR1 (0.56) | MAPTRXFP1SIGMAR1CA2MAOA | |
| SCHEMBL28753423 | 0.86 | TDP1 (0.50) | MAPTRXFP1SIGMAR1CA2MAOA | |
| SCHEMBL23015017 | 0.86 | TDP1 (0.50) | MAPTRXFP1SIGMAR1CA2MAOA | |
| SCHEMBL775567 | 0.85 | CYP1A2 (0.58) | MAPTRXFP1SIGMAR1CA2MAOA | |
| SCHEMBL27018791 | 0.85 | CYP1A2 (0.58) | CA2MAOATDP1NOS1MAOB | |
| SCHEMBL5213519 | 0.80 | SIGMAR1 (0.48) | MAPTRXFP1SIGMAR1CA2MAOA | |
| SCHEMBL23014992 | 0.80 | SIGMAR1 (0.50) | MAPTRXFP1SIGMAR1CA2MAOA | |
| SCHEMBL12040641 | 0.80 | SIGMAR1 (0.50) | MAPTRXFP1SIGMAR1CA2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210355548-A1 | SPECIFIC EXPRESSION OF HALF-TRNA IN CANCERS | THOMAS JEFFERSON UNIVERSITY (US) | 2021-11-18 | — | — | US | disclosed |