Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.31 |
| ▸ | ABAT | P80404 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 2/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13571237 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TSHREGFRKDM4EPTGS2 | |
| SCHEMBL24025436 | 0.75 | SRC (0.34) | ALDH1A1TSHRTYRCYP1A2SLC22A12 | |
| SCHEMBL13571069 | 0.75 | ALDH1A1 (0.37) | ALDH1A1TSHREGFRKDM4EPTGS2 | |
| SCHEMBL18252784 | 0.74 | TSHR (0.47) | ALDH1A1TSHRKDM4ERAB9ACYP1A2 | |
| SCHEMBL13570798 | 0.71 | TYR (0.42) | ALDH1A1TSHREGFRTYRKDM4E | |
| SCHEMBL24025458 | 0.71 | SRC (0.44) | — | |
| SCHEMBL24025598 | 0.71 | GLA (0.33) | — | |
| SCHEMBL24025456 | 0.71 | SRC (0.35) | TYRCYP1A2 | |
| SCHEMBL6899726 | 0.69 | ALDH1A1 (0.47) | ALDH1A1TSHREGFRKDM4EPTGS2 | |
| SCHEMBL13630983 | 0.69 | ALDH1A1 (0.40) | ALDH1A1TSHREGFRKDM4EPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210356473-A1 | SOLID-PHASE N-TERMINAL PEPTIDE CAPTURE AND RELEASE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210356473-A1 | SOLID-PHASE N-TERMINAL PEPTIDE CAPTURE AND RELEASE | ANPEP, MAX, DNPEP | ALDH1A1 4880/4885TSHR 1034/4885EGFR 1351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.