SCHEMBL2402628

SCHEMBL2402628

O=C(O)CCCC(CCCC(=O)O)(CCCC(=O)O)C(CO)(CO)CO

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CAMK2A Q9UQM7 1/20 0.48
LMNA P02545 4/20 0.48
SLC22A6 Q4U2R8 2/20 0.48
TSHR P16473 5/20 0.46
NFKB1 P19838 2/20 0.46
PMP22 Q01453 1/20 0.46
GPR84 Q9NQS5 4/20 0.44
FFAR1 O14842 2/20 0.44
FFAR4 Q5NUL3 2/20 0.44
HDAC11 Q96DB2 4/20 0.40
KMT2A Q03164 2/20 0.40
GABRR3 A8MPY1 1/20 0.40
GABRP O00591 1/20 0.40
GABRD O14764 1/20 0.40
HDAC3 O15379 1/20 0.40
GABBR2 O75899 1/20 0.40
CYP1A2 P05177 1/20 0.40
THRB P10828 1/20 0.40
GABRA1 P14867 1/20 0.40
GABRB1 P18505 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11857314 0.91 TSHR (0.55) CAMK2ALMNASLC22A6TSHRNFKB1
SCHEMBL5067192 0.81 GPR84 (0.52) CAMK2ALMNASLC22A6TSHRNFKB1
SCHEMBL2478421 0.81 GPR84 (0.52) CAMK2ALMNASLC22A6TSHRNFKB1
SCHEMBL8976329 0.81 GPR84 (0.52) CAMK2ALMNASLC22A6TSHRNFKB1
SCHEMBL5608497 0.81 GPR84 (0.52) CAMK2ALMNASLC22A6TSHRNFKB1
SCHEMBL1838831 0.81 GPR84 (0.52) CAMK2ALMNASLC22A6TSHRNFKB1
SCHEMBL464727 0.81 GPR84 (0.52) CAMK2ALMNASLC22A6TSHRNFKB1
SCHEMBL10818472 0.81 GPR84 (0.52) CAMK2ALMNASLC22A6TSHRNFKB1
SCHEMBL5159274 0.81 GPR84 (0.52) CAMK2ALMNASLC22A6TSHRNFKB1
SCHEMBL6054782 0.81 GPR84 (0.52) CAMK2ALMNASLC22A6TSHRNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2740497-B1 Medical adhesive compound AESCULAP AG (DE) 2017-12-06 EP disclosed
EP-2366721-B1 Medical kit for use during negative pressure wound therapy AESCULAP AG (DE) 2016-08-10 EP disclosed
EP-2223706-B1 Medical adhesive compound AESCULAP AG (DE) 2014-09-03 EP disclosed
EP-2740497-A1 Medical adhesive compound Aesculap AG (DE) 2014-06-11 EP disclosed
EP-2366721-A1 Medical kit for use during negative pressure wound therapy AESCULAP AG (DE) 2011-09-21 EP disclosed
EP-2223706-A2 Medical adhesive compound Aesculap AG (DE) 2010-09-01 EP disclosed
EP-2142223-A2 KIT FOR APPLYING A POLYMERISABLE ADHESIVE COMPOSITION TO TISSUES Henkel AG & Co. KGaA (DE) 2010-01-13 EP disclosed
EP-2137275-A1 RAPIDLY CURING CYANACRYLATES AS ADHESIVES Henkel AG & Co. KGaA (DE) 2009-12-30 EP disclosed
EP-2109646-A1 CYANOACRYLIC ACID ESTER ADHESIVE CONTAINING POLYESTER AND A PLASTICIZER Henkel AG & Co. KGaA (DE) 2009-10-21 EP disclosed
EP-2041232-A1 ADHESIVE MIXTURES HAVING POLYACRYLNITRILE Henkel AG & Co. KGaA (DE) 2009-04-01 EP disclosed
EP-1702016-B1 GAP-BRIDGING CYANOACRYLATE ADHESIVE HENKEL AG & CO KGAA (DE) 2008-07-02 EP disclosed
WO-2008006694-A1 ADHESIVE MIXTURES HAVING POLYACRYLNITRILE HENKEL AG & CO. KGAA (DE) 2008-01-17 WO disclosed
EP-1702016-A1 GAP-BRIDGING CYANOACRYLATE ADHESIVE Henkel Kommanditgesellschaft auf Aktien (DE) 2006-09-20 EP disclosed
EP-1034230-B1 CYANACRYLATE ADHESIVE WITH ESTER AND POLYMER ADDITIVES HENKEL KGAA (DE) 2005-10-12 EP disclosed
WO-2005066296-A1 GAP-BRIDGING CYANOACRYLATE ADHESIVE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-07-21 WO disclosed
EP-0904328-B1 CYANACRYLATE ADHESIVE HENKEL KGAA (DE) 2002-07-31 EP disclosed
EP-1034230-A1 CYANACRYLATE ADHESIVE WITH ESTER AND POLYMER ADDITIVES Henkel Kommanditgesellschaft auf Aktien (DE) 2000-09-13 EP disclosed
WO-1999028399-A1 CYANACRYLATE ADHESIVE WITH ESTER AND POLYMER ADDITIVES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1999-06-10 WO disclosed
EP-0904328-A1 CYANACRYLATE ADHESIVE Henkel Kommanditgesellschaft auf Aktien (DE) 1999-03-31 EP disclosed
WO-1997046630-A1 CYANACRYLATE ADHESIVE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1997-12-11 WO disclosed