Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ADA | P00813 | 5/20 | 0.34 |
| ▸ | PDE2A | O00408 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25911374 | 0.89 | ADORA2A (0.52) | SLC29A1ADORA2AADORA2BADORA1CDK1 | |
| SCHEMBL17863687 | 0.83 | CDK2 (0.54) | ADORA2AADORA2BADORA1CDK1CDK2 | |
| SCHEMBL18479940 | 0.76 | HPRT1 (0.52) | SLC29A1TSHRALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL21264900 | 0.75 | CDK1 (0.54) | ADORA2AADORA2BADORA1CDK1CDK2 | |
| SCHEMBL23710627 | 0.74 | CDK1 (0.36) | ADORA2AADORA2BADORA1CDK1CDK2 | |
| SCHEMBL15313370 | 0.74 | CDK1 (0.49) | ADORA2AADORA2BADORA1CDK1CDK2 | |
| SCHEMBL27748107 | 0.73 | CDK1 (0.54) | SLC29A1ADORA2AADORA2BADORA1CDK1 | |
| SCHEMBL18512915 | 0.72 | AHCY (0.40) | CDK1CDK2CCNB1CCNE1ALDH1A1 | |
| SCHEMBL23619296 | 0.71 | HPRT1 (0.46) | SLC29A1ADORA2AADORA2BADORA1LMNA | |
| SCHEMBL24474429 | 0.71 | KDM4E (0.39) | ADORA2AADORA2BADORA1CDK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11208414-B2 | Ectonucleotidase inhibitors and methods of use thereof | CALITHERA BIOSCIENCES, INC. (US) | 2021-12-28 | — | — | US | disclosed |
| US-11174261-B2 | — | — | 2021-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11174261-B2 | — | ENTPD5, NT5E, ENTPD1 | SLC29A1 78/4885ADORA2A 9/4885ADORA2B 35/4885 |
| US-11208414-B2 | Ectonucleotidase inhibitors and methods of use thereof | ENTPD5, NT5E, ENTPD1 | SLC29A1 71/4885ADORA2A 11/4885ADORA2B 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.