SCHEMBL2402863

SCHEMBL2402863

O=[PH](O)C(O)c1ccccc1.[CaH2]

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.44
MAPK1 P28482 1/20 0.44
SRC P12931 2/20 0.41
CYP2D6 P10635 1/20 0.41
CES2 O00748 2/20 0.40
CES1 P23141 2/20 0.40
TSHR P16473 1/20 0.38
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4540849 1.00 LMNA (0.44) LMNAMAPK1SRCCYP2D6CES2
SCHEMBL3175944 1.00 LMNA (0.44) LMNAMAPK1SRCCYP2D6CES2
SCHEMBL21723253 0.98 LMNA (0.46) LMNAMAPK1SRCCYP2D6CES2
SCHEMBL6421419 0.98 LMNA (0.46) LMNAMAPK1SRCCYP2D6CES2
SCHEMBL9036 0.98 LMNA (0.46) LMNAMAPK1SRCCYP2D6CES2
Benzene SCHEMBL23120173 0.98 LMNA (0.46) LMNAMAPK1SRCCYP2D6CES2
SCHEMBL15941285 0.98 LMNA (0.46) LMNAMAPK1SRCCYP2D6CES2
Hydrochloric Acid SCHEMBL22230828 0.95 LMNA (0.44) LMNAMAPK1SRCCYP2D6CES2
SCHEMBL22470066 0.95 LMNA (0.44) LMNAMAPK1SRCCYP2D6CES2
SCHEMBL10451600 0.95 LMNA (0.44) LMNAMAPK1SRCCYP2D6CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4355306-A1 GRANULATE COMPOSITION COMPRISING NILOTINIB Helm AG (DE) 2024-04-24 EP claimed
WO-2022263510-A1 GRANULATE COMPOSITION COMPRISING NILOTINIB HELM AG (DE) 2022-12-22 WO claimed
EP-0578768-A1 INGESTIBLE PHARMACEUTICAL COMPOSITIONS FOR TREATING UPPER GASTROINTESTINAL TRACT DISTRESS. PROCTER & GAMBLE (US) 1994-01-19 EP claimed
WO-1992017164-A1 INGESTIBLE PHARMACEUTICAL COMPOSITIONS FOR TREATING UPPER GASTROINTESTINAL TRACT DISTRESS THE PROCTER & GAMBLE COMPANY (US) 1992-10-15 WO claimed
EP-0467948-A1 COMPOSITE CERAMIC MATERIAL AND METHOD TO MANUFACTURE THE MATERIAL. STIFTELSEN CT FOER DENTALTEKNI (SE) 1992-01-29 EP claimed
WO-1991009093-A1 FLAME RETARDANT IMPREGNATION SOLUTION AND THE USE OF THE SOLUTION PYROTITE CORPORATION (US) 1991-06-27 WO claimed
WO-1990011979-A1 COMPOSITE CERAMIC MATERIAL AND METHOD TO MANUFACTURE THE MATERIAL STIFTELSEN CENTRUM FÖR DENTALTEKNIK OCH BIOMATERIAL I HUDDINGE (SE) 1990-10-18 WO claimed
EP-0363352-A1 SOLID CALCIUM PHOSPHATE MATERIALS. FARRIS EDWARD T (US) 1990-04-18 EP claimed
WO-1988009769-A1 SOLID CALCIUM PHOSPHATE MATERIALS FARRIS EDWARD T (US) 1988-12-15 WO claimed
EP-0253357-A2 Benefaction of concrete and aggregate using calcium phosphate University of Windsor (CA) 1988-01-20 EP claimed
JP-62116781-A None JP disclosed
JP-2222835-A None JP disclosed
JP-56015550-A None JP disclosed
JP-6237984-A None JP disclosed
EP-4373474-A1 BILAYER TABLET COMPRISING TELMISARTAN AND INDAPAMIDE KRKA, D.D., Novo Mesto (SI) 2024-05-29 EP disclosed
JP-S62116781-A FORMATION OF CALCIUM PHOSPHATE FILM AGENCY OF IND SCIENCE & TECHNOL 1987-05-28 JP disclosed
EP-0219078-A1 Self-hardenable material MITSUI TOATSU CHEMICALS, Inc. (JP) 1987-04-22 EP disclosed
WO-1985003437-A1 DIFFUSION COATED MULTIPLE-UNITS DOSAGE FORM A/S ALFRED BENZON (DK) 1985-08-15 WO disclosed
JP-S5615550-A REFLECTIVE FLUORESCENT LAMP MATSUSHITA ELECTRONICS CORP 1981-02-14 JP disclosed
US-4069350-A WITH CORN, FISH AND BONE MEALS AND MOLASSES, SHELL AND SALT MONSOD JR GODOFREDO G 1978-01-17 US disclosed