Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24029354 | 0.82 | POLB (0.41) | POLBMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL24029049 | 0.71 | POLB (0.66) | POLBMEN1KMT2ASLC22A12PDE4D | |
| SCHEMBL24029349 | 0.66 | RXFP1 (0.61) | POLBMEN1KMT2AGAARXFP1 | |
| SCHEMBL109451 | 0.60 | CA1 (0.61) | ALDH1A1 | |
| SCHEMBL13979875 | 0.60 | CA1 (0.47) | MEN1KMT2AALDH1A1 | |
| SCHEMBL1185621 | 0.59 | ALDH1A1 (0.63) | ALDH1A1MAPT | |
| SCHEMBL29032101 | 0.58 | HSP90AA1 (0.62) | ALDH1A1 | |
| SCHEMBL1704550 | 0.57 | CYP2D6 (0.73) | POLBMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL38810 | 0.57 | CA12 (0.59) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL1900302 | 0.57 | MPI (0.70) | ALDH1A1MAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021229035-A1 | UBIQUITIN-LIGASE INHIBITORS FOR THE TREATMENT OF CANCER | FUNDACIÓN PROFESOR NOVOA SANTOS (ES) | 2021-11-18 | — | — | WO | disclosed |