Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | RRM1 | P23921 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23568385 | 0.95 | FAAH (0.38) | FAAHKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL25697264 | 0.92 | EPHX2 (0.43) | FAAHKMT2AMEN1LMNATSHR | |
| SCHEMBL24508251 | 0.92 | EPHX2 (0.43) | FAAHKMT2AMEN1LMNATSHR | |
| SCHEMBL24673243 | 0.89 | FAAH (0.43) | FAAHKMT2AMEN1CASP2ALDH1A1 | |
| SCHEMBL21106814 | 0.85 | FAAH (0.44) | FAAHKMT2AMEN1CASP2ALDH1A1 | |
| SCHEMBL21107462 | 0.85 | FAAH (0.44) | FAAHKMT2AMEN1CASP2ALDH1A1 | |
| SCHEMBL21106815 | 0.85 | FAAH (0.44) | FAAHKMT2AMEN1CASP2ALDH1A1 | |
| SCHEMBL22856479 | 0.85 | KMT2A (0.50) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL23695885 | 0.85 | KMT2A (0.50) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL22861669 | 0.83 | KMT2A (0.61) | FAAHKMT2AMEN1CASP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278759-A1 | MK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |
| WO-2021231778-A1 | CORONAVIRUS PROTEASE DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-11-18 | — | — | WO | disclosed |