SCHEMBL24029686

SCHEMBL24029686

c1ccc2c(-c3ccc(N(c4ccc5c6ccccc6c6ccccc6c5c4)c4cc5ccccc5c5ccccc45)cc3)cccc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.39
ACMSD Q8TDX5 1/20 0.39
CA12 O43570 3/20 0.38
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
CA9 Q16790 3/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
ENPP3 O14638 1/20 0.36
ENPP1 P22413 1/20 0.36
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA7 P36544 1/20 0.35
HPRT1 P00492 3/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
CASP1 P29466 1/20 0.35
HIF1A Q16665 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24029682 0.99 CA12 (0.40) MCL1ACMSDCA12CA1CA2
SCHEMBL25730813 0.94 ALDH1A1 (0.41) MCL1ACMSDCA12CA1CA2
SCHEMBL804607 0.94 CA12 (0.42) MCL1ACMSDCA12CA1CA2
SCHEMBL22671882 0.93 CA12 (0.43) MCL1ACMSDCA12CA1CA2
SCHEMBL25088882 0.93 CA12 (0.42) MCL1ACMSDCA12CA1CA2
SCHEMBL25089137 0.93 HPRT1 (0.40) MCL1ACMSDCA12CA1CA2
SCHEMBL12159641 0.93 CA12 (0.44) MCL1ACMSDCA12CA1CA2
SCHEMBL24029689 0.92 CA12 (0.43) MCL1ACMSDCA12CA1CA2
SCHEMBL22671839 0.92 CA12 (0.40) MCL1ACMSDCA12CA1CA2
SCHEMBL22671683 0.90 MCL1 (0.38) MCL1ACMSDCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021261907-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2021-12-30 WO disclosed
WO-2021230715-A1 ORGANIC LIGHT-EMITTING ELEMENT 주식회사 엘지화학 2021-11-18 WO disclosed