Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LY6K | Q17RY6 | 2/20 | 1.00 |
| ▸ | RAD52 | P43351 | 5/20 | 0.81 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.81 |
| ▸ | KDM1A | O60341 | 3/20 | 0.79 |
| ▸ | GLA | P06280 | 2/20 | 0.79 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.79 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.79 |
| ▸ | CASP1 | P29466 | 2/20 | 0.79 |
| ▸ | CASP7 | P55210 | 2/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.79 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.79 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.79 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.79 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.79 |
| ▸ | TP53 | P04637 | 1/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.79 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.79 |
| ▸ | TOP1 | P11387 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22401407 | 0.97 | LY6K (0.94) | LY6KRAD52NCOA3KDM1AGLA | |
| Amsacrine SCHEMBL28336991 | 0.88 | TOP2B (1.00) | LY6KRAD52NCOA3KDM1AGLA | |
| Amsacrine SCHEMBL29350869 | 0.88 | TOP2B (1.00) | LY6KRAD52NCOA3KDM1AGLA | |
| Amsacrine SCHEMBL6256280 | 0.88 | TOP2B (1.00) | LY6KRAD52NCOA3KDM1AGLA | |
| Amsacrine SCHEMBL29360354 | 0.88 | TOP2B (1.00) | LY6KRAD52NCOA3KDM1AGLA | |
| Amsacrine SCHEMBL4047 | 0.88 | TOP2B (1.00) | LY6KRAD52NCOA3KDM1AGLA | |
| Amsacrine SCHEMBL31316257 | 0.87 | KMT2A (1.00) | LY6KRAD52NCOA3KDM1AGLA | |
| Amsacrine SCHEMBL1320825 | 0.87 | KMT2A (1.00) | LY6KRAD52NCOA3KDM1AGLA | |
| Amsacrine SCHEMBL31237896 | 0.86 | TOP2B (0.95) | LY6KRAD52NCOA3KDM1AGLA | |
| Amsacrine SCHEMBL2920983 | 0.86 | TOP2B (0.95) | LY6KRAD52NCOA3KDM1AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210841-A1 | COMPOUNDS FOR INHIBITING LY6K AND METHODS OF USING SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-07-06 | — | — | US | disclosed |
| US-20230210841-A1 | COMPOUNDS FOR INHIBITING LY6K AND METHODS OF USING SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-07-06 | — | — | US | disclosed |
| WO-2021231893-A1 | COMPOUNDS FOR INHIBITING LY6K AND METHODS OF USING SAME | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (US) | 2021-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210841-A1 | COMPOUNDS FOR INHIBITING LY6K AND METHODS OF USING SAME | LY6K, CD74, LY96 | LY6K 1/4885RAD52 2845/4885NCOA3 743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.