⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19706765 | 0.91 | — | — | |
| SCHEMBL13625564 | 0.67 | — | — | |
| SCHEMBL133753 | 0.66 | — | — | |
| SCHEMBL789496 | 0.66 | — | — | |
| SCHEMBL133752 | 0.66 | — | — | |
| SCHEMBL20247524 | 0.65 | — | — | |
| SCHEMBL10400467 | 0.64 | — | — | |
| SCHEMBL10400470 | 0.64 | — | — | |
| SCHEMBL17892833 | 0.63 | CHRNB2 (0.45) | — | |
| SCHEMBL12729994 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021231615-A1 | SUBSTITUTED PYRIDAZINONE FOR USE IN THE TREATMENT OF NEUROMUSCULAR DISEASES | EDGEWISE THERAPEUTICS, INC. (US) | 2021-11-18 | — | — | WO | disclosed |